Cited 12 times in
Association between low-grade albuminuria and cardiovascular risk in Korean adults: the 2011-2012 Korea National Health and Nutrition Examination Survey
DC Field | Value | Language |
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dc.contributor.author | 구철룡 | - |
dc.date.accessioned | 2018-10-02T16:40:13Z | - |
dc.date.available | 2018-10-02T16:40:13Z | - |
dc.date.issued | 2015 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/163345 | - |
dc.description.abstract | BACKGROUND: Recent studies have indicated that low UACR levels (<30 μg/mg) previously considered to be in the normal range ('low-grade albuminuria') are associated with cardiovascular morbidity and mortality in the general population. METHODS: We studied 9,736 participants with albuminuria in the normal range from the 2011-2012 Korea National Health and Nutrition Examination Survey (KNHANES). RESULTS: The weighted prevalences of metabolic syndrome (MS) and the 10-year risk for coronary heart disease measured using the Framingham risk score (FRS) ≥ 20% (high risk) were 22.5 ± 0.7% and 14.5 ± 0.7%, respectively, in males and 23.3 ± 0.8% and 8.5 ± 0.4%, respectively in females. Weighted comparisons among the tertiles of UACR revealed that the prevalences of MS and high-risk FRS increased with increasing UACR (MS: males, 15.9 ± 1.1, 20.2 ± 1.2, 32.4 ± 1.5%, respectively; P < 0.001; and females, 17.6 ± 1.0, 22.7 ± 1.0, 30.2 ± 1.4%, respectively; P < 0.001. High-risk FRS: males, 9.5 ± 0.7, 12.3 ± 0.9, 22.5 ± 1.2, respectively; P < 0.001; and females, 5.8 ± 0.6, 7.9 ± 0.7, 12.0 ± 0.9%, respectively; P < 0.001). The positive association persisted after adjusting for hypertension and diabetes. The weighted comparisons among the deciles of UACR revealed that the prevalences of MS and high-risk FRS began to increase at the ranges of 3.89-5.15 and 5.16-7.36 mg/g Cr, respectively. CONCLUSION: Low-grade albuminuria was significantly associated with estimated cardiovascular risk and MS in a nationally representative sample of Koreans. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Public Library of Science | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Albuminuria/epidemiology* | - |
dc.subject.MESH | Cardiovascular Diseases/epidemiology* | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Metabolic Syndrome/epidemiology | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Nutrition Surveys | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Risk Factors | - |
dc.title | Association between low-grade albuminuria and cardiovascular risk in Korean adults: the 2011-2012 Korea National Health and Nutrition Examination Survey | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Jae Won Hong | - |
dc.contributor.googleauthor | Cheol Ryong Ku | - |
dc.contributor.googleauthor | Jung Hyun Noh | - |
dc.contributor.googleauthor | Kyung Soo Ko | - |
dc.contributor.googleauthor | Byoung Doo Rhee | - |
dc.contributor.googleauthor | Dong-Jun Kim | - |
dc.identifier.doi | 10.1371/journal.pone.0118866 | - |
dc.contributor.localId | A00201 | - |
dc.relation.journalcode | J02540 | - |
dc.identifier.eissn | 1932-6203 | - |
dc.identifier.pmid | 25742159 | - |
dc.contributor.alternativeName | Ku, Cheol Ryong | - |
dc.contributor.affiliatedAuthor | Ku, Cheol Ryong | - |
dc.citation.volume | 10 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | e0118866 | - |
dc.identifier.bibliographicCitation | PLOS ONE, Vol.10(3) : e0118866, 2015 | - |
dc.identifier.rimsid | 60337 | - |
dc.type.rims | ART | - |
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