Cited 18 times in
Effects of dietary antioxidant vitamins on lung functions according to gender and smoking status in Korea: a population-based cross-sectional study
DC Field | Value | Language |
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dc.contributor.author | 김영삼 | - |
dc.date.accessioned | 2018-09-28T08:50:32Z | - |
dc.date.available | 2018-09-28T08:50:32Z | - |
dc.date.issued | 2018 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/163139 | - |
dc.description.abstract | OBJECTIVE: Cigarette smoke-induced oxidative stress plays an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Dietary antioxidants are thought to prevent smoke-induced oxidative damage. The aim of this study was to investigate associations between lung function and the consumption of antioxidant vitamins in Korean adults. METHODS: In total, 21 148 participants from the Korean National Health and Nutrition Examination Survey (2007-2014) were divided into four groups based on smoking history and gender. Multivariate regression models were used to evaluate associations between lung function and intake of dietary antioxidants. RESULTS: Subjects in the highest intake quintile (Q5) of vitamin A, carotene and vitamin C intake had mean forced expiratory volume in 1 s (FEV1) measurements that were 30 mL, 32 mL and 36 mL higher than those of individuals in the lowest intake quintile (Q1), respectively (p for trend; p=0.008, p=0.010 and p<0.001, respectively). The risks of COPD for male smokers in Q1 increased 7.60-fold (95% CI 5.92 to 9.76), 7.16-fold (95% CI 5.58 to 9.19) and 7.79-fold (95% CI 6.12 to 9.92), for vitamin A, carotene and vitamin C, respectively, compared with those of female non-smokers in Q5. Among patients with COPD, men who smoked >20 pack-years had mean FEV1 measurements that were 192 mL, 149 mL and 177 mL higher than those of patients in Q1 (p for trend; p=0.018, p=0.024 and p=0.043, for vitamin A, carotene and vitamin C, respectively). CONCLUSIONS: These findings indicate that the influence of antioxidant vitamins on lung function depends on gender and smoking status in the Korean COPD population. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | BMJ Publishing Group Ltd | - |
dc.relation.isPartOf | BMJ OPEN | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Effects of dietary antioxidant vitamins on lung functions according to gender and smoking status in Korea: a population-based cross-sectional study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Ji Young Hong | - |
dc.contributor.googleauthor | Chang Youl Lee | - |
dc.contributor.googleauthor | Myung Goo Lee | - |
dc.contributor.googleauthor | Young Sam Kim | - |
dc.identifier.doi | 10.1136/bmjopen-2017-020656 | - |
dc.contributor.localId | A00707 | - |
dc.relation.journalcode | J00380 | - |
dc.identifier.eissn | 2044-6055 | - |
dc.identifier.pmid | 29627816 | - |
dc.subject.keyword | antioxidant vitamins | - |
dc.subject.keyword | gender | - |
dc.subject.keyword | lung function | - |
dc.subject.keyword | smoking | - |
dc.contributor.alternativeName | Kim, Young Sam | - |
dc.contributor.affiliatedAuthor | Kim, Young Sam | - |
dc.citation.volume | 8 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | e020656 | - |
dc.identifier.bibliographicCitation | BMJ OPEN, Vol.8(4) : e020656, 2018 | - |
dc.identifier.rimsid | 58410 | - |
dc.type.rims | ART | - |
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