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Prognostic value of pre-transplant mean pulmonary arterial pressure in lung transplant recipients: a single-institution experience

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dc.contributor.author강영애-
dc.contributor.author김송이-
dc.contributor.author김영삼-
dc.contributor.author김은영-
dc.contributor.author김치영-
dc.contributor.author박무석-
dc.contributor.author박지은-
dc.contributor.author백효채-
dc.contributor.author송주한-
dc.contributor.author이진구-
dc.contributor.author임아영-
dc.contributor.author장준-
dc.contributor.author정경수-
dc.contributor.author정지예-
dc.date.accessioned2018-08-28T17:29:30Z-
dc.date.available2018-08-28T17:29:30Z-
dc.date.issued2018-
dc.identifier.issn2072-1439-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/162671-
dc.description.abstractBackground: Currently, lung transplantation (LTX) is considered to be a curative treatment option in patients with end-stage lung disease. Although pulmonary hypertension (PH), confirmed by cardiac catheterization, is a prognostic factor in patients undergoing LTX, the prognostic value of PH in Asian lung transplant recipients remains uncertain. In this study, we aimed to determine whether PH before LTX may serve as a prognostic factor for survival in Asian patients. Methods: The medical records of 50 patients [male, 27; female, 23; mean age, 51.0 (41.0-60.0) years], who received preoperative right heart catheterization (RHC) and echocardiography before single or double LTX at Severance Hospital between January 2010 and December 2014, were reviewed. The relationship between 1-year survival after LTX and PH [mean pulmonary arterial pressure (mPAP) >/=25 mmHg at rest] was evaluated. Results: The mean right ventricular systolic pressure and mPAP were 48.5 (22.8) and 30.0 (24.0-40.0) mmHg. Of the 50 patients, 17 (34.0%) died within a year after LTX. The 1-year survival rate among patients with mPAP >/=25 mmHg (58.8%) was lower than the survival rate among patients with mPAP <25 mmHg (87.5%). Pre-transplantation mPAP of >/=25 mmHg was associated with post-transplantation survival [hazard ratio (HR), 4.832; 95% confidence interval (CI), 1.080-21.608, P=0.039]. The presence of preoperative PH was also associated with an increased risk of postoperative complications. Conclusions: Confirmation of PH via preoperative cardiac catheterization was associated with the prognosis of the patient after LTX. Clinicians should consider the necessity for early transplantation surgery before the mPAP reaches >/=25 mmHg.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherPioneer Bioscience Pub. Co.-
dc.relation.isPartOfJournal of Thoracic Disease-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titlePrognostic value of pre-transplant mean pulmonary arterial pressure in lung transplant recipients: a single-institution experience-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorChi Young Kim-
dc.contributor.googleauthorJi Eun Park-
dc.contributor.googleauthorAh Young Leem-
dc.contributor.googleauthorJoo Han Song-
dc.contributor.googleauthorSong Yee Kim-
dc.contributor.googleauthorKyung Soo Chung-
dc.contributor.googleauthorEun Young Kim-
dc.contributor.googleauthorJi Ye Jung-
dc.contributor.googleauthorYoung Ae Kang-
dc.contributor.googleauthorYoung Sam Kim-
dc.contributor.googleauthorJoon Chang-
dc.contributor.googleauthorJin Gu Lee-
dc.contributor.googleauthorHyo Chae Paik-
dc.contributor.googleauthorMoo Suk Park-
dc.identifier.doi10.21037/jtd.2018.03.46-
dc.contributor.localIdA00057-
dc.contributor.localIdA00626-
dc.contributor.localIdA00707-
dc.contributor.localIdA00811-
dc.contributor.localIdA04916-
dc.contributor.localIdA01457-
dc.contributor.localIdA05476-
dc.contributor.localIdA01846-
dc.contributor.localIdA02062-
dc.contributor.localIdA03225-
dc.contributor.localIdA03382-
dc.contributor.localIdA03472-
dc.contributor.localIdA03570-
dc.contributor.localIdA03735-
dc.relation.journalcodeJ01907-
dc.identifier.eissn2077-6624-
dc.identifier.pmid29707309-
dc.subject.keywordLung transplantation (LTX)-
dc.subject.keywordhypertension-
dc.subject.keywordprognosis-
dc.subject.keywordpulmonary-
dc.contributor.alternativeNameKang, Young Ae-
dc.contributor.alternativeNameKim, Song Yi-
dc.contributor.alternativeNameKim, Young Sam-
dc.contributor.alternativeNameKim, Eun Young-
dc.contributor.alternativeNameKim, Chi Young-
dc.contributor.alternativeNamePark, Moo Suk-
dc.contributor.alternativeNamePark, Ji Eun-
dc.contributor.alternativeNamePaik, Hyo Chae-
dc.contributor.alternativeNameSong, Joo Han-
dc.contributor.alternativeNameLee, Jin Gu-
dc.contributor.alternativeNameLeem, Ah Young-
dc.contributor.alternativeNameChang, Joon-
dc.contributor.alternativeNameJung, Kyung Soo-
dc.contributor.alternativeNameJung, Ji Ye-
dc.contributor.affiliatedAuthorKang, Young Ae-
dc.contributor.affiliatedAuthorKim, Song Yi-
dc.contributor.affiliatedAuthorKim, Young Sam-
dc.contributor.affiliatedAuthorKim, Eun Young-
dc.contributor.affiliatedAuthorKim, Chi Young-
dc.contributor.affiliatedAuthorPark, Moo Suk-
dc.contributor.affiliatedAuthorPark, Ji Eun-
dc.contributor.affiliatedAuthorPaik, Hyo Chae-
dc.contributor.affiliatedAuthorSong, Joo Han-
dc.contributor.affiliatedAuthorLee, Jin Gu-
dc.contributor.affiliatedAuthorLeem, Ah Young-
dc.contributor.affiliatedAuthorChang, Joon-
dc.contributor.affiliatedAuthorJung, Kyung Soo-
dc.contributor.affiliatedAuthorJung, Ji Ye-
dc.citation.volume10-
dc.citation.number3-
dc.citation.startPage1578-
dc.citation.endPage1587-
dc.identifier.bibliographicCitationJournal of Thoracic Disease, Vol.10(3) : 1578-1587, 2018-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers

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