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Cardiovascular involvement in systemic rheumatic diseases: An integrated view for the treating physicians
DC Field | Value | Language |
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dc.contributor.author | 신재일 | - |
dc.contributor.author | 이금화 | - |
dc.contributor.author | 이광섭 | - |
dc.date.accessioned | 2018-08-28T17:17:07Z | - |
dc.date.available | 2018-08-28T17:17:07Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1568-9972 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/162448 | - |
dc.description.abstract | Systemic autoimmune diseases can affect various kinds of organs including the kidney, the skin, soft tissue and the bone. Among others, cardiovascular involvement in rheumatic diseases has been shown to affect myocardium, pericardium, cardiac vessels, conduction system and valves, eventually leading to increased mortality. In general, underlying chronic inflammation leads to premature atherosclerosis, but also other manifestations such as arrhythmia and heart failure may have a 'silent' progress. Traditional cardiovascular risk factors play a secondary role, while disease-specific factors (i.e. disease duration, severity, antibody positivity, persistent disease activity) can directly influence the cardiovascular system. Therefore, early diagnosis is critical to optimize management and to control inflammatory activity and recent data suggest that risk factors (i.e. hypercholesterolemia and hypertension) need intensive treatment as well. With the advent of immunosuppressive agents, most rheumatic diseases are well controlled on treatment, but information related to their cardioprotective efficacy is not well-defined. In this review, we focus on cardiovascular involvement in rheumatic diseases and highlight current evidence which should be of help for the treating physicians. Moreover, cardiotoxicity of immunosuppressive drugs is a rare issue and such potential adverse events will be briefly discussed. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | AUTOIMMUNITY REVIEWS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Cardiovascular Diseases/*etiology/pathology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Physicians/*standards | - |
dc.subject.MESH | Rheumatic Diseases/*complications/pathology | - |
dc.subject.MESH | Risk Factors | - |
dc.title | Cardiovascular involvement in systemic rheumatic diseases: An integrated view for the treating physicians | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Pediatrics | - |
dc.contributor.googleauthor | Kwang Seob Lee | - |
dc.contributor.googleauthor | Andreas Kronbichler | - |
dc.contributor.googleauthor | Michael Eisenhut | - |
dc.contributor.googleauthor | Keum Hwa Lee | - |
dc.contributor.googleauthor | Jae Il Shin | - |
dc.identifier.doi | 10.1016/j.autrev.2017.12.001 | - |
dc.contributor.localId | A02142 | - |
dc.contributor.localId | A04622 | - |
dc.relation.journalcode | J03068 | - |
dc.identifier.eissn | 1873-0183 | - |
dc.identifier.pmid | 29353099 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S1568997218300041 | - |
dc.subject.keyword | Cardiovascular involvement | - |
dc.subject.keyword | Disease-modifying anti-rheumatic drug | - |
dc.subject.keyword | Systemic rheumatic disease | - |
dc.subject.keyword | Toxicity | - |
dc.contributor.alternativeName | Shin, Jae Il | - |
dc.contributor.alternativeName | Lee, Geum Hwa | - |
dc.contributor.affiliatedAuthor | Shin, Jae Il | - |
dc.contributor.affiliatedAuthor | Lee, Geum Hwa | - |
dc.citation.volume | 17 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 201 | - |
dc.citation.endPage | 214 | - |
dc.identifier.bibliographicCitation | AUTOIMMUNITY REVIEWS, Vol.17(3) : 201-214, 2018 | - |
dc.identifier.rimsid | 60030 | - |
dc.type.rims | ART | - |
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