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Stone heterogeneity index on single-energy noncontrast computed tomography can be a positive predictor of urinary stone composition

Authors
 Jong Soo Lee  ;  Kang Su Cho  ;  Seung Hwan Lee  ;  Young Eun Yoon  ;  Dong Hyuk Kang  ;  Won Sik Jeong  ;  Hae Do Jung  ;  Jong Kyou Kwon  ;  Joo Yong Lee 
Citation
 PLOS ONE, Vol.13(4) : e0193945, 2018 
Journal Title
 PLOS ONE 
Issue Date
2018
MeSH
Adult ; Aged ; Female ; Humans ; Kidney Calculi/*diagnostic imaging ; Male ; Middle Aged ; Retrospective Studies ; X-Ray Computed Tomography ; Urinary Calculi/*diagnostic imaging ; Urinary Tract/*diagnostic imaging
Abstract
The aim of this study was to investigate the correlation between stone composition and single-energy noncontrast computed tomography (NCCT) parameters, including stone heterogeneity index (SHI) and mean stone density (MSD), in patients with urinary calculi. We retrospectively reviewed medical records of 255 patients who underwent operations or procedures for urinary stones or had spontaneous stone passage between December 2014 and October 2015. Among these, 214 patients with urinary calculi who underwent NCCT and stone composition analyses were included in the study. Maximal stone length (MSL), mean stone density (MSD), and stone heterogeneity index (SHI) were determined on pretreatment NCCT. The mean MSD (454.68+/-177.80 HU) and SHI (115.82+/-96.31 HU) of uric acid stones were lower than those of all other types. Based on post hoc tests, MSD was lower for uric acid stones than for the other types (vs. CaOx: P<0.001; vs. infection stones: P<0.001). SHI was lower for uric acid stones than for the other types (vs. CaOx: P<0.001; vs. infection stones: P<0.001) Receiver operating characteristic curves of uric acid stones for MSD and SHI demonstrated that SHI (cut-off value: 140.4 HU) was superior to MSD (cut-off value: 572.3 HU) in predicting uric acid stones (P<0.001).
Files in This Item:
T201801153.pdf Download
DOI
10.1371/journal.pone.0193945
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Kang, Dong Hyuk(강동혁)
Yoon, Young Eun(윤영은)
Lee, Seung Hwan(이승환) ORCID logo https://orcid.org/0000-0001-7358-8544
Lee, Jong Soo(이종수) ORCID logo https://orcid.org/0000-0002-9984-1138
Lee, Joo Yong(이주용) ORCID logo https://orcid.org/0000-0002-3470-1767
Jeong, Won Sik(정원식)
Jung, Hae Do(정해도)
Cho, Kang Su(조강수) ORCID logo https://orcid.org/0000-0002-3500-8833
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/162216
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