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Current medical treatment of uterine fibroids

DC FieldValueLanguage
dc.contributor.author손금선-
dc.contributor.author조시현-
dc.date.accessioned2018-08-28T17:03:10Z-
dc.date.available2018-08-28T17:03:10Z-
dc.date.issued2018-
dc.identifier.issn2287-8572-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/162206-
dc.description.abstractUterine fibroids (leiomyomas or myomas), benign monoclonal tumors, are the most common benign tumors in women. Heavy or prolonged menstrual bleeding, abnormal uterine bleeding, resultant anemia, pelvic pain, infertility, and/or recurrent pregnancy loss are generally associated with uterine fibroids. Although curative treatment of this tumor relies on surgical therapies, medical treatments are considered the first-line treatment to preserve fertility and avoid or delay surgery. The aim of this review is to provide available and emerging medical treatment options for symptomatic uterine fibroids. Literature review and consensus of expert opinion. Many uterine fibroids are asymptomatic and require no intervention, although it is advisable to follow-up patients to document stability in size and growth. Fibroid-associated symptoms include heavy menstrual bleeding and pain or pelvic discomfort. The association between infertility and fibroids increases with age. Treatment options for symptomatic uterine fibroids - include medical, surgical, and radiologically guided interventions. Various medical therapies are now available for women with uterine fibroids, although each therapy has its own advantages and disadvantages. Currently, gonadotrophin-releasing hormone (GnRH) agonists and selective progesterone receptor modulators (SPRMs) are the most effective medical therapies, with the most evidence to support their reduction of fibroid volume and symptomatic improvement in menstrual bleeding. The choice of treatment depends on the patient's personal treatment goals, as well as efficacy and need for repeated interventions.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Society of Obstetrics and Gynecology-
dc.relation.isPartOfObstetrics & Gynecology Science-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleCurrent medical treatment of uterine fibroids-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Obstetrics & Gynecology-
dc.contributor.googleauthorGeum Seon Sohn-
dc.contributor.googleauthorSiHyun Cho-
dc.contributor.googleauthorYong Man Kim-
dc.contributor.googleauthorChi-Heum Cho-
dc.contributor.googleauthorMee-Ran Kim-
dc.contributor.googleauthorSa Ra Lee-
dc.identifier.doi10.5468/ogs.2018.61.2.192-
dc.contributor.localIdA05478-
dc.contributor.localIdA03846-
dc.relation.journalcodeJ02408-
dc.identifier.eissn2287-8580-
dc.identifier.pmid29564309-
dc.subject.keywordGnRH receptor-
dc.subject.keywordUterine fibroids-
dc.contributor.alternativeNameSohn, Geum Seon-
dc.contributor.alternativeNameCho, Si Hyun-
dc.contributor.affiliatedAuthorSohn, Geum Seon-
dc.contributor.affiliatedAuthorCho, Si Hyun-
dc.citation.volume61-
dc.citation.number2-
dc.citation.startPage192-
dc.citation.endPage201-
dc.identifier.bibliographicCitationObstetrics & Gynecology Science, Vol.61(2) : 192-201, 2018-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers

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