Cited 20 times in
Estimated Prevalence of Adolescents with Nonalcoholic Fatty Liver Disease in Korea
DC Field | Value | Language |
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dc.contributor.author | 강윤구 | - |
dc.contributor.author | 고홍 | - |
dc.contributor.author | 김승 | - |
dc.contributor.author | 박소원 | - |
dc.date.accessioned | 2018-08-28T17:01:02Z | - |
dc.date.available | 2018-08-28T17:01:02Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/162170 | - |
dc.description.abstract | BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) has become prevalent worldwide in the last decade. However, the recent prevalence of NAFLD in adolescents has not yet been investigated in Korea. METHODS: Data were obtained from 1,416 participants aged 10-18 years from the Korea National Health and Nutrition Examination Survey conducted in 2010 and 2015. Systolic blood pressure (SBP), diastolic blood pressure (DBP), height, weight, waist circumference (WC), body mass index (BMI), fasting glucose, total cholesterol, high-density lipoprotein (HDL), aspartate aminotransferase (AST), alanine aminotransferase (ALT) level, waist-to-height ratio (WHtR), and pediatric NAFLD fibrosis index (PNFI) were analyzed. RESULTS: SBP, weight, WC, BMI, WHtR, and total cholesterol level were significantly higher in 2015 than in 2010. Prevalence of NAFLD (BMI >/= 85th percentile plus ALT > 30 U/L for boys and ALT > 19 U/L for girls) were 4.7% in 2010 and 5.9% in 2015 (P = 0.360). Using various cutoffs for the ALT level (> 40, > 30, > 25.8 U/L for boys and >22.1 U/L for girls) NAFLD prevalence rates were 3.0%, 4.1%, and 5.5% in 2010; 2.9%, 5.0%, and 7.1% in 2015, respectively (P = 0.899, 0.469, and 0.289). Boys had a higher SBP, DBP, height, weight, WC, BMI, WHtR, fasting glucose, total cholesterol, ALT, and lower HDL level than girls. The probability of liver fibrosis using the PNFI varies between 21.3% and 24.5% among NAFLD participants (P < 0.001). CONCLUSION: The Korean society needs to quickly control the increasing prevalence of NAFLD in adolescents and reduce its complications. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | 대한의학회(The Korean Academy of Medical Sciences) | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Estimated Prevalence of Adolescents with Nonalcoholic Fatty Liver Disease in Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Pediatrics | - |
dc.contributor.googleauthor | Yunkoo Kang | - |
dc.contributor.googleauthor | Sowon Park | - |
dc.contributor.googleauthor | Seung Kim | - |
dc.contributor.googleauthor | Hong Koh | - |
dc.identifier.doi | 10.3346/jkms.2018.33.e109 | - |
dc.contributor.localId | A05213 | - |
dc.contributor.localId | A00156 | - |
dc.contributor.localId | A00651 | - |
dc.contributor.localId | A05216 | - |
dc.relation.journalcode | J01517 | - |
dc.identifier.eissn | 1598-6357 | - |
dc.identifier.pmid | 29607635 | - |
dc.subject.keyword | Adolescents | - |
dc.subject.keyword | Estimated | - |
dc.subject.keyword | Korea | - |
dc.subject.keyword | Nonalcoholic Fatty Liver Disease | - |
dc.subject.keyword | Prevalence | - |
dc.contributor.alternativeName | Kang, Yunkoo | - |
dc.contributor.alternativeName | Koh, Hong | - |
dc.contributor.alternativeName | Kim, Seung | - |
dc.contributor.alternativeName | Park, So Won | - |
dc.contributor.affiliatedAuthor | Kang, Yunkoo | - |
dc.contributor.affiliatedAuthor | Koh, Hong | - |
dc.contributor.affiliatedAuthor | Kim, Seung | - |
dc.contributor.affiliatedAuthor | Park, So Won | - |
dc.citation.volume | 33 | - |
dc.citation.number | 14 | - |
dc.citation.startPage | e109 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.33(14) : e109, 2018 | - |
dc.identifier.rimsid | 59758 | - |
dc.type.rims | ART | - |
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