The purpose of this study was to evaluate the shear bond strengths between various hybrid computer-aided
design (CAD)/computer-aided manufacturing (CAM) restorative materials and repairing resin. Two resin network-based
hybrid (Lava Ultimate and Polyglass), one ceramic framework-based hybrid (Enamic), and one zirconia (Zenotec
Zr bridge) CAD/CAM restorative materials were used in this study. The shear bond strength test and failure modes
of four experimental groups designated LUS (Lava Ultimate), ENA (Enamic), PGB (Polyglass), and ZBR (zirconia
control group) were characterized in this study. The hybrid CAD/CAM restorative materials showed stronger shear
bond strengths in the sequence of PGB, LUS, and ENA (P<0.05). The shear bond strengths of PGB and LUS
groups showed significantly higher than those of ZBR (P<0.05), while ENA did not show any significant difference
from ZBR (P<0.05). The PEG and LUS groups mostly exhibited cohesive failure, but the ENA and ZBR groups
predominantly showed adhesive failure. Therefore, resin network-based hybrid CAD/CAM restorative materials such
as Lava Ultimate and Polyglass should be more useful for intra-oral repairs.