Cited 11 times in
Outcomes of Rate-Control Treatment in Patients With Atrial Fibrillation and Heart Failure- A Nationwide Cohort Study
DC Field | Value | Language |
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dc.contributor.author | 김종윤 | - |
dc.contributor.author | 김태훈 | - |
dc.contributor.author | 박희남 | - |
dc.contributor.author | 양필성 | - |
dc.contributor.author | 엄재선 | - |
dc.contributor.author | 유승찬 | - |
dc.contributor.author | 유희태 | - |
dc.contributor.author | 이문형 | - |
dc.contributor.author | 정보영 | - |
dc.date.accessioned | 2018-08-28T16:58:48Z | - |
dc.date.available | 2018-08-28T16:58:48Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1346-9843 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/162131 | - |
dc.description.abstract | BACKGROUND: Rate control is now a front-line therapy in the management of atrial fibrillation (AF). However, the survival benefits of different rate-control medications remain controversial, so we assessed the efficacy of rate-control medications in AF patients with concomitant heart failure (HF).Methods and Results:From January 2002 to December 2008, a total of 7,034 AF patients with a single type of rate-control drug or without rate-control treatment were enrolled from the Korea National Health Insurance Service database. The death rates over a mean follow-up of 4.5+/-1.2 years were 12.6% (580 of 4,593) and 29.0% (709 of 2,441) in non-HF and HF patients, respectively. Among the total subjects, the risk of death was lower in patients receiving beta-blockers (adjusted hazard ratio (HR) 0.75, 95% confidence interval (CI) 0.64-0.88) and calcium-channel blockers (adjusted HR 0.74, 95% CI 0.55-0.98) compared with those who did not receive rate-control medications. In patients without HF, use of rate-control medications did not affect the risk of death. In patients with HF, beta-blockers significantly decreased the mortality risk (adjusted HR 0.63, 95% CI 0.50-0.79), whereas use of calcium-channel blockers or digoxin was not associated with death. The results were observed consistently among the cohorts after propensity matching. CONCLUSIONS: Use of beta-blockers was associated with a reduced mortality rate for AF patient with HF but not for those without HF. These findings should be examined in a large randomized trial. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English, Japanese | - |
dc.publisher | Japanese Circulation Society | - |
dc.relation.isPartOf | CIRCULATION JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Outcomes of Rate-Control Treatment in Patients With Atrial Fibrillation and Heart Failure- A Nationwide Cohort Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Hee Tae Yu | - |
dc.contributor.googleauthor | Pil-Sung Yang | - |
dc.contributor.googleauthor | Hancheol Lee | - |
dc.contributor.googleauthor | Seng Chan You | - |
dc.contributor.googleauthor | Tae-Hoon Kim | - |
dc.contributor.googleauthor | Jae-Sun Uhm | - |
dc.contributor.googleauthor | Jong-Youn Kim | - |
dc.contributor.googleauthor | Hui-Nam Pak | - |
dc.contributor.googleauthor | Moon-Hyoung Lee | - |
dc.contributor.googleauthor | Boyoung Joung | - |
dc.identifier.doi | 10.1253/circj.CJ-17-0669 | - |
dc.contributor.localId | A00926 | - |
dc.contributor.localId | A01085 | - |
dc.contributor.localId | A01776 | - |
dc.contributor.localId | A02323 | - |
dc.contributor.localId | A02337 | - |
dc.contributor.localId | A02478 | - |
dc.contributor.localId | A02535 | - |
dc.contributor.localId | A02766 | - |
dc.contributor.localId | A03609 | - |
dc.relation.journalcode | J00534 | - |
dc.identifier.eissn | 1347-4820 | - |
dc.identifier.pmid | 29142156 | - |
dc.subject.keyword | Atrial fibrillation | - |
dc.subject.keyword | Beta-blockers | - |
dc.subject.keyword | Calcium-channel blockers | - |
dc.subject.keyword | Digoxin | - |
dc.subject.keyword | Heart failure | - |
dc.contributor.alternativeName | Kim, Jong Youn | - |
dc.contributor.alternativeName | Kim, Tae Hoon | - |
dc.contributor.alternativeName | Pak, Hui Nam | - |
dc.contributor.alternativeName | Yang, Pil Sung | - |
dc.contributor.alternativeName | Uhm, Jae Sun | - |
dc.contributor.alternativeName | You, Seng Chan | - |
dc.contributor.alternativeName | Yu, Hee Tae | - |
dc.contributor.alternativeName | Lee, Moon Hyoung | - |
dc.contributor.alternativeName | Joung, Bo Young | - |
dc.contributor.affiliatedAuthor | Kim, Jong Youn | - |
dc.contributor.affiliatedAuthor | Kim, Tae-Hoon | - |
dc.contributor.affiliatedAuthor | Pak, Hui Nam | - |
dc.contributor.affiliatedAuthor | Yang, Pil Sung | - |
dc.contributor.affiliatedAuthor | Uhm, Jae Sun | - |
dc.contributor.affiliatedAuthor | You, Seng Chan | - |
dc.contributor.affiliatedAuthor | Yu, Hee Tae | - |
dc.contributor.affiliatedAuthor | Lee, Moon Hyoung | - |
dc.contributor.affiliatedAuthor | Joung, Bo Young | - |
dc.contributor.affiliatedAuthor | 김종윤 | - |
dc.contributor.affiliatedAuthor | 김태훈 | - |
dc.contributor.affiliatedAuthor | 박희남 | - |
dc.contributor.affiliatedAuthor | 양필성 | - |
dc.contributor.affiliatedAuthor | 엄재선 | - |
dc.contributor.affiliatedAuthor | 유승찬 | - |
dc.contributor.affiliatedAuthor | 유희태 | - |
dc.contributor.affiliatedAuthor | 이문형 | - |
dc.contributor.affiliatedAuthor | 정보영 | - |
dc.citation.volume | 82 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 652 | - |
dc.citation.endPage | 658 | - |
dc.identifier.bibliographicCitation | CIRCULATION JOURNAL, Vol.82(3) : 652-658, 2018 | - |
dc.identifier.rimsid | 59720 | - |
dc.type.rims | ART | - |
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