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The Effect of Door-to-Diuretic Time on Clinical Outcomes in Patients With Acute Heart Failure
DC Field | Value | Language |
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dc.contributor.author | 강석민 | - |
dc.contributor.author | 오재원 | - |
dc.date.accessioned | 2018-08-28T16:58:24Z | - |
dc.date.available | 2018-08-28T16:58:24Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 2213-1779 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/162126 | - |
dc.description.abstract | OBJECTIVES: This study sought to examine the impact of door-to-diuretic (D2D) time on mortality in patients with acute heart failure (AHF) who were presenting to an emergency department (ED). BACKGROUND: Most patients with AHF present with congestion. Early decongestion with diuretic agents could improve their clinical outcomes. METHODS: The Korea Acute Heart Failure registry enrolled 5,625 consecutive patients hospitalized for AHF. For this analysis, the study included patients who received intravenous diuretic agents within 24 h after ED arrival. Early and delayed groups were defined as D2D time </=60 min and D2D time >60 min, respectively. The primary outcomes were in-hospital death and post-discharge death at 1 month and 1 year on the basis of D2D time. RESULTS: A total of 2,761 patients met the inclusion criteria. The median D2D time was 128 min (interquartile range: 63 to 243 min), and 663 (24%) patients belonged to the early group. The baseline characteristics were similar between the groups. The rate of in-hospital death did not differ between the groups (5.0% vs. 5.1%; p > 0.999), nor did the post-discharge 1-month (4.0% vs. 3.0%; log-rank p = 0.246) and 1-year (20.6% vs. 19.3%; log-rank p = 0.458) mortality rates. Get With the Guidelines-Heart Failure risk score was calculated for each patient. In multivariate analyses with adjustment for Get With the Guidelines-Heart Failure risk score and other significant clinical covariates and propensity-matched analyses, D2D time was not associated with clinical outcomes. CONCLUSIONS: The D2D time was not associated with clinical outcomes in a large prospective cohort of patients with AHF who were presenting to an ED. (Registry [Prospective Cohort] for Heart Failure in Korea [KorAHF]; NCT01389843). | - |
dc.description.statementOfResponsibility | open | - |
dc.language | United States | - |
dc.publisher | 2213-1787 | - |
dc.relation.isPartOf | JACC-HEART FAILURE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | The Effect of Door-to-Diuretic Time on Clinical Outcomes in Patients With Acute Heart Failure | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Jin Joo Park | - |
dc.contributor.googleauthor | Sun-Hwa Kim | - |
dc.contributor.googleauthor | Il-Young Oh | - |
dc.contributor.googleauthor | Dong-Ju Choi | - |
dc.contributor.googleauthor | Hyun-Ah Park | - |
dc.contributor.googleauthor | Hyun-Jai Cho | - |
dc.contributor.googleauthor | Hae-Young Lee | - |
dc.contributor.googleauthor | Jae-Yeong Cho | - |
dc.contributor.googleauthor | Kye Hun Kim | - |
dc.contributor.googleauthor | Jung-Woo Son | - |
dc.contributor.googleauthor | Byung-Su Yoo | - |
dc.contributor.googleauthor | Jaewon Oh | - |
dc.contributor.googleauthor | Seok-Min Kang | - |
dc.contributor.googleauthor | Sang Hong Baek | - |
dc.contributor.googleauthor | Ga Yeon Lee | - |
dc.contributor.googleauthor | Jin Oh Choi | - |
dc.contributor.googleauthor | Eun-Seok Jeon | - |
dc.contributor.googleauthor | Sang Eun Lee | - |
dc.contributor.googleauthor | Jae-Joong Kim | - |
dc.contributor.googleauthor | Ju-Hee Lee | - |
dc.contributor.googleauthor | Myeong-Chan Cho | - |
dc.contributor.googleauthor | Se Yong Jang | - |
dc.contributor.googleauthor | Shung Chull Chae | - |
dc.contributor.googleauthor | Byung-Hee Oh | - |
dc.identifier.doi | 10.1016/j.jchf.2017.12.017 | - |
dc.contributor.localId | A00037 | - |
dc.contributor.localId | A02395 | - |
dc.relation.journalcode | J03351 | - |
dc.identifier.eissn | 2213-1787 | - |
dc.identifier.pmid | 29598933 | - |
dc.subject.keyword | acute heart failure | - |
dc.subject.keyword | door-to-diuretic time | - |
dc.subject.keyword | outcomes | - |
dc.contributor.alternativeName | Kang, Seok Min | - |
dc.contributor.alternativeName | Oh, Jae Won | - |
dc.contributor.affiliatedAuthor | Kang, Seok Min | - |
dc.contributor.affiliatedAuthor | Oh, Jae Won | - |
dc.citation.volume | 6 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 286 | - |
dc.citation.endPage | 294 | - |
dc.identifier.bibliographicCitation | JACC-HEART FAILURE, Vol.6(4) : 286-294, 2018 | - |
dc.identifier.rimsid | 59715 | - |
dc.type.rims | ART | - |
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