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Predictors of Long-Term Outcomes of Percutaneous Mitral Valvuloplasty in Patients with Rheumatic Mitral Stenosis.

DC FieldValueLanguage
dc.contributor.author김다래-
dc.contributor.author김중선-
dc.contributor.author남종호-
dc.contributor.author박동혁-
dc.contributor.author심지영-
dc.contributor.author장혁재-
dc.contributor.author하종원-
dc.contributor.author홍그루-
dc.date.accessioned2018-08-28T16:54:05Z-
dc.date.available2018-08-28T16:54:05Z-
dc.date.issued2018-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/162049-
dc.description.abstractPURPOSE: We determined factors associated with long-term outcomes of patients who underwent successful percutaneous mitral balloon valvuloplasty (PMV). MATERIALS AND METHODS: Between August 1980 and May 2013, 1187 patients underwent PMV at Severance Hospital, Seoul, Korea. A total of 742 patients who underwent regular clinic visits for more than 10 years were retrospectively analyzed. The endpoints consisted of repeated PMV, mitral valve (MV) surgery, and cardiovascular-related death. RESULTS: The optimal result, defined as a post-PMV mitral valve area (MVA) >1.5 cm² and mitral regurgitation ≤Grade II, was obtained in 631 (85%) patients. Over a mean follow up duration of 214±50 months, 54 (7.3%) patients underwent repeat PMV, 4 (0.5%) underwent trido-PMV, and 248 (33.4%) underwent MV surgery. A total of 33 patients (4.4%) had stroke, and 35 (4.7%) patients died from cardiovascular-related reasons. In a multivariate analysis, echocardiographic score [p=0.003, hazard ratio=1.56, 95% confidence interval (CI): 1.01-2.41] and post-MVA cut-off (p<0.001, relative risk=0.39, 95% CI: 0.37-0.69) were the only significant predictors of long-term clinical outcomes after adjusting for confounding variables. A post-MVA cut-off value of 1.76 cm² showed satisfactory predictive power for poor long-term clinical outcomes. CONCLUSION: In this long-term follow up study (up to 20 years), an echocardiographic score >8 and post-MVA ≤1.76 cm² were independent predictors of poor long-term clinical outcomes after PMV, including MV reintervention, stroke, and cardiovascular-related death-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHCatheterization*-
dc.subject.MESHEchocardiography-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHKaplan-Meier Estimate-
dc.subject.MESHMale-
dc.subject.MESHMitral Valve Stenosis/diagnostic imaging-
dc.subject.MESHMitral Valve Stenosis/surgery*-
dc.subject.MESHMultivariate Analysis-
dc.subject.MESHProportional Hazards Models-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHTime Factors-
dc.subject.MESHTreatment Outcome-
dc.titlePredictors of Long-Term Outcomes of Percutaneous Mitral Valvuloplasty in Patients with Rheumatic Mitral Stenosis.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorDarae Kim-
dc.contributor.googleauthorHyemoon Chung-
dc.contributor.googleauthorJong-Ho Nam-
dc.contributor.googleauthorDong Hyuk Park-
dc.contributor.googleauthorChi Young Shim-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorHyuk-Jae Chang-
dc.contributor.googleauthorGeu-Ru Hong-
dc.contributor.googleauthorJong-Won Ha-
dc.identifier.doi10.3349/ymj.2018.59.2.273-
dc.contributor.localIdA00361-
dc.contributor.localIdA00961-
dc.contributor.localIdA05468-
dc.contributor.localIdA01455-
dc.contributor.localIdA02213-
dc.contributor.localIdA03490-
dc.contributor.localIdA04257-
dc.contributor.localIdA04386-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid29436196-
dc.subject.keywordMitral stenosis-
dc.subject.keywordoutcome-
dc.subject.keywordpercutaneous mitral balloon valvuloplasty-
dc.contributor.alternativeNameKim, Da Rae-
dc.contributor.alternativeNameKim, Jung Sun-
dc.contributor.alternativeNameNam, Jong-Ho-
dc.contributor.alternativeNamePark, Dong Hyuk-
dc.contributor.alternativeNameShim, Chi Young-
dc.contributor.alternativeNameChang, Hyuck Jae-
dc.contributor.alternativeNameHa, Jong Won-
dc.contributor.alternativeNameHong, Geu Ru-
dc.contributor.affiliatedAuthorKim, Da Rae-
dc.contributor.affiliatedAuthorKim, Jung Sun-
dc.contributor.affiliatedAuthorNam, Jong-Ho-
dc.contributor.affiliatedAuthorPark, Dong Hyuk-
dc.contributor.affiliatedAuthorShim, Chi Young-
dc.contributor.affiliatedAuthorChang, Hyuck Jae-
dc.contributor.affiliatedAuthorHa, Jong Won-
dc.contributor.affiliatedAuthorHong, Geu Ru-
dc.citation.volume59-
dc.citation.number2-
dc.citation.startPage273-
dc.citation.endPage278-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.59(2) : 273-278, 2018-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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