Cited 29 times in
Effects of continuous positive airway pressure therapy on left ventricular diastolic function: a randomised, sham-controlled clinical trial
DC Field | Value | Language |
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dc.contributor.author | 김다래 | - |
dc.contributor.author | 박성하 | - |
dc.contributor.author | 심지영 | - |
dc.contributor.author | 조양제 | - |
dc.contributor.author | 조형주 | - |
dc.contributor.author | 하종원 | - |
dc.contributor.author | 홍그루 | - |
dc.date.accessioned | 2018-08-28T16:53:13Z | - |
dc.date.available | 2018-08-28T16:53:13Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0903-1936 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/162038 | - |
dc.description.abstract | Continuous positive airway pressure (CPAP) therapy may decrease left ventricular (LV) loads and improve myocardial oxygenation. In this study, we investigated the effect of CPAP on LV diastolic function compared with sham treatment in patients with severe obstructive sleep apnoea (OSA).This 3-month prospective single-centre randomised sham-controlled trial analysed 52 patients with severe OSA. Patients were randomly assigned (1:1) to receive either CPAP or sham treatment for 3 months. The main investigator and patients were masked to the trial randomisation. The primary end-point was change of early diastolic mitral annular (e') velocity over the 3-month period. Secondary end-points were pulse wave velocity (PWV), 24-h ambulatory blood pressure (BP) and variables of ventricular-vascular coupling at 3 months.After 3 months of follow-up, CPAP treatment significantly increased the e' velocity, and was greater than the sham treatment (0.65+/-1.70 versus -0.61+/-1.85 cm.s(-1), p=0.014). The PWV, 24-h mean diastolic BP, night-time diastolic BP, arterial elastance index and ventricular-vascular coupling index after 3 months of follow-up decreased significantly in the CPAP group.In patients with severe OSA, CPAP treatment for 3 months improved LV diastolic function more than sham treatment, and was accompanied by improvements in arterial stiffness and ventricular-vascular coupling. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | European Respiratory Society | - |
dc.relation.isPartOf | EUROPEAN RESPIRATORY JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Effects of continuous positive airway pressure therapy on left ventricular diastolic function: a randomised, sham-controlled clinical trial | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Chi Young Shim | - |
dc.contributor.googleauthor | Darae Kim | - |
dc.contributor.googleauthor | Sungha Park | - |
dc.contributor.googleauthor | Chan Joo Lee | - |
dc.contributor.googleauthor | Hyung-Ju Cho | - |
dc.contributor.googleauthor | Jong-Won Ha | - |
dc.contributor.googleauthor | Yang-Je Cho | - |
dc.contributor.googleauthor | Geu-Ru Hong | - |
dc.identifier.doi | 10.1183/13993003.01774-2017 | - |
dc.contributor.localId | A00361 | - |
dc.contributor.localId | A01512 | - |
dc.contributor.localId | A02213 | - |
dc.contributor.localId | A03851 | - |
dc.contributor.localId | A03936 | - |
dc.contributor.localId | A04257 | - |
dc.contributor.localId | A04386 | - |
dc.relation.journalcode | J00852 | - |
dc.identifier.eissn | 1399-3003 | - |
dc.identifier.pmid | 29386335 | - |
dc.identifier.url | http://erj.ersjournals.com/content/51/2/1701774 | - |
dc.contributor.alternativeName | Kim, Da Rae | - |
dc.contributor.alternativeName | Park, Sung Ha | - |
dc.contributor.alternativeName | Shim, Chi Young | - |
dc.contributor.alternativeName | Cho, Yang Je | - |
dc.contributor.alternativeName | Cho, Hyung Ju | - |
dc.contributor.alternativeName | Ha, Jong Won | - |
dc.contributor.alternativeName | Hong, Geu Ru | - |
dc.contributor.affiliatedAuthor | Kim, Da Rae | - |
dc.contributor.affiliatedAuthor | Park, Sung Ha | - |
dc.contributor.affiliatedAuthor | Shim, Chi Young | - |
dc.contributor.affiliatedAuthor | Cho, Yang Je | - |
dc.contributor.affiliatedAuthor | Cho, Hyung Ju | - |
dc.contributor.affiliatedAuthor | Ha, Jong Won | - |
dc.contributor.affiliatedAuthor | Hong, Geu Ru | - |
dc.citation.volume | 51 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 1701774 | - |
dc.identifier.bibliographicCitation | EUROPEAN RESPIRATORY JOURNAL, Vol.51(2) : 1701774, 2018 | - |
dc.identifier.rimsid | 59628 | - |
dc.type.rims | ART | - |
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