Cited 32 times in
The combined exposure to intra-amniotic inflammation and neonatal respiratory distress syndrome increases the risk of intraventricular hemorrhage in preterm neonates
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이준호 | - |
dc.date.accessioned | 2018-08-28T16:51:07Z | - |
dc.date.available | 2018-08-28T16:51:07Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0300-5577 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/162006 | - |
dc.description.abstract | OBJECTIVE: To evaluate the impact of combined exposure to intra-amniotic inflammation and neonatal respiratory distress syndrome (RDS) on the development of intraventricular hemorrhage (IVH) in preterm neonates. METHODS: This retrospective cohort study includes 207 consecutive preterm births (24.0-33.0 weeks of gestation). Intra-amniotic inflammation was defined as an amniotic fluid matrix metalloproteinase-8 concentration >23 ng/mL. According to McMenamin's classification, IVH was defined as grade II or higher when detected by neurosonography within the first weeks of life. RESULTS: (1) IVH was diagnosed in 6.8% (14/207) of neonates in the study population; (2) IVH was frequent among newborns exposed to intra-amniotic inflammation when followed by postnatal RDS [33% (6/18)]. The frequency of IVH was 7% (8/115) among neonates exposed to either of these conditions - intra-amniotic inflammation or RDS - and 0% (0/64) among those who were not exposed to these conditions; and (3) Neonates exposed to intra-amniotic inflammation and postnatal RDS had a significantly higher risk of IVH than those with only intra-amniotic inflammation [odds ratio (OR) 4.6, 95% confidence interval (CI) 1.1-19.3] and those with RDS alone (OR 5.6, 95% CI 1.0-30.9), after adjusting for gestational age. CONCLUSION: The combined exposure to intra-amniotic inflammation and postnatal RDS markedly increased the risk of IVH in preterm neonates. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Walter De Gruyter | - |
dc.relation.isPartOf | JOURNAL OF PERINATAL MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | The combined exposure to intra-amniotic inflammation and neonatal respiratory distress syndrome increases the risk of intraventricular hemorrhage in preterm neonates | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Obstetrics & Gynecology | - |
dc.contributor.googleauthor | Kyung Joon Oh | - |
dc.contributor.googleauthor | Jee Yoon Park | - |
dc.contributor.googleauthor | JoonHo Lee | - |
dc.contributor.googleauthor | Joon-Seok Hong | - |
dc.contributor.googleauthor | Roberto Romero | - |
dc.contributor.googleauthor | Bo Hyun Yoon | - |
dc.identifier.doi | 10.1515/jpm-2016-0348 | - |
dc.contributor.localId | A04846 | - |
dc.relation.journalcode | J01693 | - |
dc.identifier.eissn | 1619-3997 | - |
dc.identifier.pmid | 28672753 | - |
dc.subject.keyword | Brain injury | - |
dc.subject.keyword | hypoxic-ischemic injury | - |
dc.subject.keyword | intra-amniotic inflammation | - |
dc.subject.keyword | periventricular-intraventricular hemorrhage | - |
dc.subject.keyword | preterm birth | - |
dc.contributor.alternativeName | Lee, Joon Ho | - |
dc.contributor.affiliatedAuthor | Lee, Joon Ho | - |
dc.citation.volume | 46 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 43363 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PERINATAL MEDICINE, Vol.46(1) : 43363, 2018 | - |
dc.identifier.rimsid | 59596 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.