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Predicting new-onset diabetes after minimally invasive subtotal distal pancreatectomy in benign and borderline malignant lesions of the pancreas

DC Field Value Language
dc.contributor.author강창무-
dc.contributor.author이우정-
dc.contributor.author황호경-
dc.date.accessioned2018-07-20T11:57:19Z-
dc.date.available2018-07-20T11:57:19Z-
dc.date.issued2017-
dc.identifier.issn0025-7974-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/161544-
dc.description.abstractThe purpose of this study was to evaluate the time-dependent probability and risk factors of pancreatogenic diabetes mellitus (PDM) in patients who underwent minimally invasive subtotal distal pancreatectomy.Changes in glucose metabolic consequence of 34 patients (laparoscopic: 31, robotic: 3) who underwent surgery from December 2005 to December 2014 were estimated by assessing impaired fasting glucose, PDM, and PDM-free time analysis.A total of 22 patients showed glucose intolerance, including 13 (38.2%) with impaired fasting glucose and 9 (26.5%) with PDM. The median onset time of PDM was 6.8 months (range 5.3-13.2 months). The PDM-free time probability according to time interval was 94.1% (6 months), 75.9% (12 months), and 72.6% (18 months). It was shown that body mass index>23 kg/m (49.9 vs 87.9 months, P = .020) and preoperative cholesterol >200 mg/dL (40.9 vs 85.2 months, P = .003) adversely influenced PDM-free time. Preoperative cholesterol >200 mg/dL (hazard ratio = 6.172; 95% confidence interval, 1.532-24.865; P = .010) was significantly associated with short PDM-free time in Cox proportional hazards model.Patients with high cholesterol levels and high BMI should be closely monitored for the development of PDM.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherLippincott Williams & Wilkins-
dc.relation.isPartOfMEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBlood Glucose/analysis-
dc.subject.MESHCholesterol/blood-
dc.subject.MESHDiabetes Mellitus/etiology-
dc.subject.MESHFemale-
dc.subject.MESHGlucose Intolerance/etiology-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMinimally Invasive Surgical Procedures/adverse effects-
dc.subject.MESHMinimally Invasive Surgical Procedures/methods-
dc.subject.MESHPancreatectomy/adverse effects-
dc.subject.MESHPancreatectomy/methods-
dc.subject.MESHPancreatic Neoplasms/surgery-
dc.subject.MESHProportional Hazards Models-
dc.subject.MESHRisk Factors-
dc.subject.MESHTime Factors-
dc.titlePredicting new-onset diabetes after minimally invasive subtotal distal pancreatectomy in benign and borderline malignant lesions of the pancreas-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Surgery-
dc.contributor.googleauthorHo Kyoung Hwang-
dc.contributor.googleauthorJiae Park-
dc.contributor.googleauthorSung Hoon Choi-
dc.contributor.googleauthorChang Moo Kang-
dc.contributor.googleauthorWoo Jung Lee-
dc.identifier.doi10.1097/MD.0000000000009404-
dc.contributor.localIdA00088-
dc.contributor.localIdA02993-
dc.contributor.localIdA04497-
dc.relation.journalcodeJ02214-
dc.identifier.eissn1536-5964-
dc.identifier.pmid29390555-
dc.contributor.alternativeNameKang, Chang Moo-
dc.contributor.alternativeNameLee, Woo Jung-
dc.contributor.alternativeNameHwang, Ho Kyoung-
dc.contributor.affiliatedAuthorKang, Chang Moo-
dc.contributor.affiliatedAuthorLee, Woo Jung-
dc.contributor.affiliatedAuthorHwang, Ho Kyoung-
dc.citation.volume96-
dc.citation.number51-
dc.citation.startPagee9404-
dc.identifier.bibliographicCitationMEDICINE, Vol.96(51) : e9404, 2017-
dc.identifier.rimsid61574-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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