Cited 46 times in
Association between fasting glucose and all-cause mortality according to sex and age: a prospective cohort study
DC Field | Value | Language |
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dc.contributor.author | 이용호 | - |
dc.date.accessioned | 2018-07-20T11:56:37Z | - |
dc.date.available | 2018-07-20T11:56:37Z | - |
dc.date.issued | 2017 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/161527 | - |
dc.description.abstract | The association of fasting glucose with the risk of death according to sex and age remains unclear, and insufficient information is available on sex- and age-specific glucose concentrations within ethnic groups. This study analyzed a sample of 12,455,361 Korean adults who participated in health examinations during 2001-2004, and were followed up until 2013. Men had 3.0 mg/dL (0.167 mmol/L) higher mean glucose concentrations than women (94.7 vs. 91.7 mg/dL), although women over 73 years had higher levels. For glucose levels of 100-199 mg/dL, each 18 mg/dL (1 mmol/L) increase in fasting glucose increased mortality by 13% (HR = 1.13, [95% CI 1.12 to 1.13], p < 0.001). In individuals with fasting glucose levels of 100-125 mg/dL, each 18 mg/dL increase in fasting glucose was associated with a 30% increase in the risk for mortality (1.30, [1.18 to 1.43]) in those aged 18-34 years, a 32% increase (1.32, [1.26 to 1.39]) in those aged 35-44 years, and a 10% increase (1.10, [1.02 to 1.19]) in those aged 75-99 years. The fasting glucose levels associated with the lowest mortality were 80-94 mg/dL regardless of sex and age. Prediabetes (100-125 mg/dL) was associated with higher mortality. The associations of hyperglycemia with mortality were stronger at younger ages. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Nature Publishing Group | - |
dc.relation.isPartOf | SCIENTIFIC REPORTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Association between fasting glucose and all-cause mortality according to sex and age: a prospective cohort study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Sang-Wook Yi | - |
dc.contributor.googleauthor | Sangkyu Park | - |
dc.contributor.googleauthor | Yong-ho Lee | - |
dc.contributor.googleauthor | Hyang-Jeong Park | - |
dc.contributor.googleauthor | Beverley Balkau | - |
dc.contributor.googleauthor | Jee-Jeon Yi | - |
dc.identifier.doi | 10.1038/s41598-017-08498-6 | - |
dc.contributor.localId | A02989 | - |
dc.relation.journalcode | J02646 | - |
dc.identifier.eissn | 2045-2322 | - |
dc.identifier.pmid | 28811570 | - |
dc.contributor.alternativeName | Lee, Yong Ho | - |
dc.contributor.affiliatedAuthor | Lee, Yong Ho | - |
dc.citation.volume | 7 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 8194 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, Vol.7(1) : 8194, 2017 | - |
dc.identifier.rimsid | 61432 | - |
dc.type.rims | ART | - |
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