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Association between fasting glucose and all-cause mortality according to sex and age: a prospective cohort study

DC Field Value Language
dc.contributor.author이용호-
dc.date.accessioned2018-07-20T11:56:37Z-
dc.date.available2018-07-20T11:56:37Z-
dc.date.issued2017-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/161527-
dc.description.abstractThe association of fasting glucose with the risk of death according to sex and age remains unclear, and insufficient information is available on sex- and age-specific glucose concentrations within ethnic groups. This study analyzed a sample of 12,455,361 Korean adults who participated in health examinations during 2001-2004, and were followed up until 2013. Men had 3.0 mg/dL (0.167 mmol/L) higher mean glucose concentrations than women (94.7 vs. 91.7 mg/dL), although women over 73 years had higher levels. For glucose levels of 100-199 mg/dL, each 18 mg/dL (1 mmol/L) increase in fasting glucose increased mortality by 13% (HR = 1.13, [95% CI 1.12 to 1.13], p < 0.001). In individuals with fasting glucose levels of 100-125 mg/dL, each 18 mg/dL increase in fasting glucose was associated with a 30% increase in the risk for mortality (1.30, [1.18 to 1.43]) in those aged 18-34 years, a 32% increase (1.32, [1.26 to 1.39]) in those aged 35-44 years, and a 10% increase (1.10, [1.02 to 1.19]) in those aged 75-99 years. The fasting glucose levels associated with the lowest mortality were 80-94 mg/dL regardless of sex and age. Prediabetes (100-125 mg/dL) was associated with higher mortality. The associations of hyperglycemia with mortality were stronger at younger ages.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherNature Publishing Group-
dc.relation.isPartOfSCIENTIFIC REPORTS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleAssociation between fasting glucose and all-cause mortality according to sex and age: a prospective cohort study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorSang-Wook Yi-
dc.contributor.googleauthorSangkyu Park-
dc.contributor.googleauthorYong-ho Lee-
dc.contributor.googleauthorHyang-Jeong Park-
dc.contributor.googleauthorBeverley Balkau-
dc.contributor.googleauthorJee-Jeon Yi-
dc.identifier.doi10.1038/s41598-017-08498-6-
dc.contributor.localIdA02989-
dc.relation.journalcodeJ02646-
dc.identifier.eissn2045-2322-
dc.identifier.pmid28811570-
dc.contributor.alternativeNameLee, Yong Ho-
dc.contributor.affiliatedAuthorLee, Yong Ho-
dc.citation.volume7-
dc.citation.number1-
dc.citation.startPage8194-
dc.identifier.bibliographicCitationSCIENTIFIC REPORTS, Vol.7(1) : 8194, 2017-
dc.identifier.rimsid61432-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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