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The 23-year tracking of blood lipids from adolescence to adulthood in Korea: the Kangwha study

DC FieldValueLanguage
dc.contributor.author김현창-
dc.contributor.author서일-
dc.date.accessioned2018-07-20T11:55:55Z-
dc.date.available2018-07-20T11:55:55Z-
dc.date.issued2017-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/161510-
dc.description.abstractBACKGROUND: Several studies have examined tracking pattern of blood lipids level during long follow-up periods in Western countries. However, there have been few such studies in Asian populations. METHODS: The Kangwha Study is a community-based prospective cohort study that started in 1986 on Kangwha Island, South Korea. A total of 432 participants (47% men) were enrolled in the study, during which serum total cholesterol, triglycerides, and high-density lipoprotein (HDL) cholesterol levels were measured for each participant at least once during adolescence (12-16 years of age) and again at least once during adulthood (25-35 years of age). The tracking patterns of the blood lipid levels were determined using Spearman correlation coefficients and tracking coefficients from generalized estimating equations. RESULTS: The Spearman correlation coefficients between lipid measurements ranged from 0.12 to 0.73 depending on the lipid profile and measurement time interval; all were significant (p < 0.05). The magnitude of the coefficients tended to decrease as the time interval increased. When adjusted for age, sex, body mass index, and blood pressure, the tracking coefficients were 0.58 (95% confidence interval [CI]: 0.54-0.63) for total cholesterol, 0.39 (95% CI: 0.31-0.48) for triglycerides, and 0.51 (95% CI: 0.47-0.56) for HDL cholesterol. In a subgroup analysis by sex, the tracking coefficients were higher for women than for men, except for HDL cholesterol. CONCLUSIONS: The tracking patterns of blood lipids from adolescence to adulthood were notable. This study supports the importance of measuring lipids during adolescence for identifying high-risk individuals-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherBioMed Central-
dc.relation.isPartOfLipids in Health and Disease-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleThe 23-year tracking of blood lipids from adolescence to adulthood in Korea: the Kangwha study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Preventive Medicine-
dc.contributor.googleauthorJung Hyun Lee-
dc.contributor.googleauthorHyeon Chang Kim-
dc.contributor.googleauthorDae Ryong Kang-
dc.contributor.googleauthorIl Suh-
dc.identifier.doi10.1186/s12944-017-0615-2-
dc.contributor.localIdA01142-
dc.contributor.localIdA01899-
dc.relation.journalcodeJ02169-
dc.identifier.eissn1476-511X-
dc.identifier.pmid29166949-
dc.subject.keywordAdolescence-
dc.subject.keywordEpidemiology-
dc.subject.keywordLipids-
dc.subject.keywordRepublic of Korea-
dc.subject.keywordRisk factors-
dc.subject.keywordTracking-
dc.contributor.alternativeNameKim, Hyeon Chang-
dc.contributor.alternativeNameSuh, Il-
dc.contributor.affiliatedAuthorKim, Hyeon Chang-
dc.contributor.affiliatedAuthorSuh, Il-
dc.citation.volume16-
dc.citation.number1-
dc.citation.startPage221-
dc.identifier.bibliographicCitationLipids in Health and Disease, Vol.16(1) : 221, 2017-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Preventive Medicine and Public Health (예방의학교실) > 1. Journal Papers

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