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Combination Therapy with Capecitabine and Cisplatin as Second-Line Chemotherapy for Advanced Biliary Tract Cancer

DC FieldValueLanguage
dc.contributor.author박승우-
dc.contributor.author박정엽-
dc.contributor.author방승민-
dc.contributor.author송시영-
dc.contributor.author이희승-
dc.contributor.author정문재-
dc.contributor.author정장한-
dc.contributor.author조인래-
dc.contributor.author조중현-
dc.date.accessioned2018-07-20T11:55:13Z-
dc.date.available2018-07-20T11:55:13Z-
dc.date.issued2017-
dc.identifier.issn0009-3157-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/161497-
dc.description.abstractBACKGROUND/AIMS: Palliative chemotherapy is the main treatment for advanced biliary tract cancer (BTC). However, there is a lack of established second-line chemotherapy to treat disease progression after first-line chemotherapy. We examined combination therapy with capecitabine and cisplatin for advanced BTC as a second-line regimen. METHODS: We analyzed the medical records of 40 patients diagnosed with BTC who received palliative second-line chemotherapy with capecitabine and cisplatin. RESULTS: The median overall survival from the start of second-line chemotherapy was 6.3 months. The median overall survival from diagnosis was 17.9 months. The median progression-free survival during second-line chemotherapy was 2.3 months. Nine (30%) patients experienced adverse events of grade ≥3. Eastern Cooperative Oncology Group performance score was an independent predictor of adverse events. CONCLUSIONS: Combination therapy with capecitabine and cisplatin may be an option for second-line chemotherapy in some of patients with advanced BTC.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherKarger-
dc.relation.isPartOfCHEMOTHERAPY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleCombination Therapy with Capecitabine and Cisplatin as Second-Line Chemotherapy for Advanced Biliary Tract Cancer-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorJung J.H.-
dc.contributor.googleauthorLee H.S.-
dc.contributor.googleauthorJo J.H.-
dc.contributor.googleauthorCho I.R.-
dc.contributor.googleauthorChung M.J.-
dc.contributor.googleauthorBang S.-
dc.contributor.googleauthorPark S.W.-
dc.contributor.googleauthor· Song S.Y.-
dc.contributor.googleauthorPark J.Y.-
dc.identifier.doi10.1159/000479425-
dc.contributor.localIdA01551-
dc.contributor.localIdA01647-
dc.contributor.localIdA01786-
dc.contributor.localIdA02035-
dc.contributor.localIdA03349-
dc.contributor.localIdA03602-
dc.contributor.localIdA05182-
dc.contributor.localIdA03890-
dc.contributor.localIdA03912-
dc.relation.journalcodeJ00519-
dc.identifier.eissn1421-9794-
dc.identifier.pmid28848173-
dc.identifier.urlhttps://www.karger.com/Article/Abstract/479425-
dc.subject.keywordBiliary tract neoplasm-
dc.subject.keywordCapecitabine-
dc.subject.keywordCisplatin-
dc.subject.keywordDrug therapy-
dc.subject.keywordPalliative care-
dc.contributor.alternativeNamePark, Seung Woo-
dc.contributor.alternativeNamePark, Jeong Youp-
dc.contributor.alternativeNameBang, Seung Min-
dc.contributor.alternativeNameSong, Si Young-
dc.contributor.alternativeNameLee, Hee Seung-
dc.contributor.alternativeNameChung, Moon Jae-
dc.contributor.alternativeNameJung, Jang Han-
dc.contributor.alternativeNameCho, In Rae-
dc.contributor.alternativeNameJo, Jung Hyun-
dc.contributor.affiliatedAuthorPark, Seung Woo-
dc.contributor.affiliatedAuthorPark, Jeong Youp-
dc.contributor.affiliatedAuthorBang, Seung Min-
dc.contributor.affiliatedAuthorSong, Si Young-
dc.contributor.affiliatedAuthorLee, Hee Seung-
dc.contributor.affiliatedAuthorChung, Moon Jae-
dc.contributor.affiliatedAuthorJung, Jang Han-
dc.contributor.affiliatedAuthorCho, In Rae-
dc.contributor.affiliatedAuthorJo, Jung Hyun-
dc.citation.volume62-
dc.citation.number6-
dc.citation.startPage361-
dc.citation.endPage366-
dc.identifier.bibliographicCitationCHEMOTHERAPY, Vol.62(6) : 361-366, 2017-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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