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Prevalence of depression and suicidal ideation increases proportionally with renal function decline, beginning from early stages of chronic kidney disease.

DC FieldValueLanguage
dc.contributor.author강신욱-
dc.contributor.author기연경-
dc.contributor.author김형래-
dc.contributor.author박서현-
dc.contributor.author박정탁-
dc.contributor.author유태현-
dc.contributor.author윤창연-
dc.contributor.author윤해룡-
dc.contributor.author이미솔-
dc.contributor.author이은-
dc.contributor.author정수영-
dc.contributor.author지종현-
dc.contributor.author차민욱-
dc.contributor.author한승혁-
dc.date.accessioned2018-07-20T08:43:56Z-
dc.date.available2018-07-20T08:43:56Z-
dc.date.issued2017-
dc.identifier.issn0025-7974-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/161379-
dc.description.abstractDepression and suicidal ideation are prevalent mental health problems in patients with chronic kidney disease (CKD. However, the association between mental health problems and kidney disease has been investigated in severe cases only. Thus, this study evaluated the relationship between mental health problems and renal function in a community-based prospective cohort study comprising patients with mild to moderate kidney disease. A total of 44,938 participants who were participated in Korean National Health and Nutrition Examination Survey IV, V, and VI from 2007 to 2014 were enrolled. Estimated glomerular filtration rate (eGFR) was calculated using the CKD Epidemiology Collaboration equation. The study outcome was the prevalence of depression and suicidal ideations assessed by self-reporting surveys. Logistic regression analysis was performed to evaluate the relationship between renal function and outcomes. The mean age of the study subjects was 49.2 ± 16.6 years, and the mean eGFR was 94.0 mL/min/1.73 m. The prevalence of depression and suicidal ideation increased with decreasing eGFR. Multivariate logistic regression analysis showed that the risk of depression increased in subjects with eGFR <45 mL/min/1.73 m [odds ratio (OR) 1.47; 95% confidence interval (CI) 1.09-1.98]. The risk of suicidal ideation gradually increased in groups with eGFR <90 mL/min/1.73 m (OR, 1.11; 95% CI, 1.03-1.20), even after adjustments for confounding variables. In conclusion, depression and suicidal ideation are related closely with renal dysfunction. The risk of having depression and suicidal ideation increased even in patient with mild renal dysfunction. Therefore, evaluation and management strategies regarding mental health problems should be taken into account throughout all stages of CKD.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherLippincott Williams & Wilkins-
dc.relation.isPartOfMEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHDepression/epidemiology-
dc.subject.MESHDepression/etiology-
dc.subject.MESHDisease Progression-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNutrition Surveys-
dc.subject.MESHOdds Ratio-
dc.subject.MESHPrevalence-
dc.subject.MESHProspective Studies-
dc.subject.MESHRenal Insufficiency, Chronic/pathology-
dc.subject.MESHRenal Insufficiency, Chronic/psychology-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRisk Factors-
dc.subject.MESHSuicidal Ideation-
dc.subject.MESHTime Factors-
dc.titlePrevalence of depression and suicidal ideation increases proportionally with renal function decline, beginning from early stages of chronic kidney disease.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorJong H. Jhee-
dc.contributor.googleauthorEun Lee-
dc.contributor.googleauthorMin-Uk Cha-
dc.contributor.googleauthorMisol Lee-
dc.contributor.googleauthorHyoungnae Kim-
dc.contributor.googleauthorSeohyun Park-
dc.contributor.googleauthorHae-Ryong Yun-
dc.contributor.googleauthorSu-Young Jung-
dc.contributor.googleauthorYoun K. Kee-
dc.contributor.googleauthorChang-Yun Yoon-
dc.contributor.googleauthorSeung H. Han-
dc.contributor.googleauthorTae-Hyun Yoo-
dc.contributor.googleauthorShin-Wook Kang-
dc.contributor.googleauthorJung T. Park-
dc.identifier.doi10.1097/MD.0000000000008476-
dc.contributor.localIdA00053-
dc.contributor.localIdA00276-
dc.contributor.localIdA01147-
dc.contributor.localIdA01495-
dc.contributor.localIdA01654-
dc.contributor.localIdA02526-
dc.contributor.localIdA02613-
dc.contributor.localIdA04617-
dc.contributor.localIdA02771-
dc.contributor.localIdA03032-
dc.contributor.localIdA04667-
dc.contributor.localIdA03970-
dc.contributor.localIdA05046-
dc.contributor.localIdA04304-
dc.relation.journalcodeJ02214-
dc.identifier.eissn1536-5964-
dc.identifier.pmid29095304-
dc.contributor.alternativeNameKang, Shin Wook-
dc.contributor.alternativeNameKee, Youn Kyung-
dc.contributor.alternativeNameKim, Hyoung Rae-
dc.contributor.alternativeNamePark, Seo Hyun-
dc.contributor.alternativeNamePark, Jung Tak-
dc.contributor.alternativeNameYoo, Tae Hyun-
dc.contributor.alternativeNameYoon, Chang Yun-
dc.contributor.alternativeNameYun, Hae Ryong-
dc.contributor.alternativeNameLee, Mi Sol-
dc.contributor.alternativeNameLee, Eun-
dc.contributor.alternativeNameJung, Su Young-
dc.contributor.alternativeNameJhee, Jong Hyun-
dc.contributor.alternativeNameCha, Min Uk-
dc.contributor.alternativeNameHan, Seung Hyeok-
dc.contributor.affiliatedAuthorKang, Shin Wook-
dc.contributor.affiliatedAuthorKee, Youn Kyung-
dc.contributor.affiliatedAuthorKim, Hyoung Rae-
dc.contributor.affiliatedAuthorPark, Seo Hyun-
dc.contributor.affiliatedAuthorPark, Jung Tak-
dc.contributor.affiliatedAuthorYoo, Tae Hyun-
dc.contributor.affiliatedAuthorYoon, Chang Yun-
dc.contributor.affiliatedAuthorYun, Hae Ryong-
dc.contributor.affiliatedAuthorLee, Mi Sol-
dc.contributor.affiliatedAuthorLee, Eun-
dc.contributor.affiliatedAuthorJung, Su Young-
dc.contributor.affiliatedAuthorJhee, Jong Hyun-
dc.contributor.affiliatedAuthorCha, Min Uk-
dc.contributor.affiliatedAuthorHan, Seung Hyeok-
dc.citation.volume96-
dc.citation.number44-
dc.citation.startPagee8476-
dc.identifier.bibliographicCitationMEDICINE, Vol.96(44) : e8476, 2017-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers

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