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Echocardiographic features in patients with ANCA-associated vasculitis within 3 months before and after diagnosis

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dc.contributor.author박용범-
dc.contributor.author박은성-
dc.contributor.author송정식-
dc.contributor.author안성수-
dc.contributor.author이상원-
dc.contributor.author정승민-
dc.date.accessioned2018-07-20T08:41:17Z-
dc.date.available2018-07-20T08:41:17Z-
dc.date.issued2017-
dc.identifier.issn0770-3198-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/161360-
dc.description.abstractWe investigated the all-inclusive echocardiographic features in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) within 3 months before and after diagnosis. We reviewed the medical records of 89 AAV patients taking echocardiography and 35 age- and gender-matched controls. We collected clinical and laboratory data and echocardiographic results. We compared the variables between patients with AAV of each variant and controls and among those with microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA) and eosinophilic GPA (EGPA). The mean age and period from diagnosis to echocardiography were 54.5 years (30 men) and 1.4 months. The mean age of controls was 51.6 years. AAV patients exhibited lower mean left ventricle ejection fraction (LVEF) (64.0 vs. 69.1%, P = 0.002) and higher mean E/E' ratio (11.7 vs. 8.8, P = 0.001) and right ventricle systolic pressure (RVSP) (30.2 vs. 23.2 mm Hg, P < 0.001) than the controls. Each variant of AAV presented a different pattern of echocardiographic features in comparison with controls. MPA patients exhibited systolic and diastolic dysfunctions and pulmonary arterial hypertension more often than controls. Meanwhile, GPA patients exhibited only diastolic dysfunction, and EGPA patients had systolic dysfunction and pulmonary arterial hypertension more frequently than controls. No meaningful differences in echocardiographic features appeared among AAV variants. AAV patients exhibited reduced systolic function and advanced diastolic dysfunctions and pulmonary arterial hypertension near the time of diagnosis compared with controls. Each variant of AAV presented a different pattern in echocardiographic features.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherSpringer-
dc.relation.isPartOfCLINICAL RHEUMATOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleEchocardiographic features in patients with ANCA-associated vasculitis within 3 months before and after diagnosis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorSung Soo Ahn-
dc.contributor.googleauthorEun Seong Park-
dc.contributor.googleauthorSeung Min Jung-
dc.contributor.googleauthorJason Jungsik Song-
dc.contributor.googleauthorYong-Beom Park-
dc.contributor.googleauthorSang-Won Lee-
dc.identifier.doi10.1007/s10067-017-3868-2-
dc.contributor.localIdA01579-
dc.contributor.localIdA05128-
dc.contributor.localIdA02057-
dc.contributor.localIdA02233-
dc.contributor.localIdA02824-
dc.contributor.localIdA05179-
dc.relation.journalcodeJ00612-
dc.identifier.eissn1434-9949-
dc.identifier.pmid28988280-
dc.identifier.urlhttps://link.springer.com/article/10.1007%2Fs10067-017-3868-2-
dc.contributor.alternativeNamePark, Yong Beom-
dc.contributor.alternativeNamePark, EunSeong-
dc.contributor.alternativeNameSong, Jung Sik-
dc.contributor.alternativeNameAhn, Sung Soo-
dc.contributor.alternativeNameLee, Sang Won-
dc.contributor.alternativeNameJung, SeungMin-
dc.contributor.affiliatedAuthorPark, Yong Beom-
dc.contributor.affiliatedAuthorPark, EunSeong-
dc.contributor.affiliatedAuthorSong, Jung Sik-
dc.contributor.affiliatedAuthorAhn, Sung Soo-
dc.contributor.affiliatedAuthorLee, Sang Won-
dc.contributor.affiliatedAuthorJung, SeungMin-
dc.citation.volume36-
dc.citation.number12-
dc.citation.startPage2751-
dc.citation.endPage2759-
dc.identifier.bibliographicCitationCLINICAL RHEUMATOLOGY, Vol.36(12) : 2751-2759, 2017-
dc.identifier.rimsid61278-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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