Cited 25 times in
The relationship between visceral obesity and hepatic steatosis measured by controlled attenuation parameter.
DC Field | Value | Language |
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dc.contributor.author | 김광준 | - |
dc.contributor.author | 김창오 | - |
dc.contributor.author | 박준용 | - |
dc.contributor.author | 이혜원 | - |
dc.contributor.author | 정규식 | - |
dc.contributor.author | 정재복 | - |
dc.contributor.author | 한광협 | - |
dc.date.accessioned | 2018-07-20T08:41:04Z | - |
dc.date.available | 2018-07-20T08:41:04Z | - |
dc.date.issued | 2017 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/161358 | - |
dc.description.abstract | BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is closely related with obesity. However, obese subjects, generally represented by high BMI, do not always develop NAFLD. A number of possible causes of NAFLD have been studied, but the exact mechanism has not yet been elucidated. METHODS: A total of 304 consecutive subjects who underwent general health examinations including abdominal ultrasonography, transient elastography and abdominal fat computed tomography were prospectively enrolled. Significant steatosis was diagnosed by ultrasonography and controlled attenuation parameter (CAP) assessed by transient elastography. RESULTS: Visceral fat area (VFA) was significantly related to hepatic steatosis assessed by CAP, whereas body mass index (BMI) was related to CAP only in univariate analysis. In multiple logistic regression analysis, VFA (odds ratio [OR], 1.010; 95% confidence interval [CI], 1.001-1.019; P = 0.028) and triglycerides (TG) (OR, 1.006; 95% CI, 1.001-1.011; P = 0.022) were independent risk factors for significant hepatic steatosis. The risk of significant hepatic steatosis was higher in patients with higher VFA: the OR was 4.838 (P<0.001; 95% CI, 2.912-8.039) for 100<VFA≤200 cm2 and 7.474 (P<0.001; 95% CI, 2.462-22.693) for VFA >200 cm2, compared to patients with a VFA ≤100 cm2. CONCLUSIONS: Our data demonstrated that VFA and TG is significantly related to hepatic steatosis assessed by CAP not BMI. This finding suggests that surveillance for subjects with NAFLD should incorporate an indicator of visceral obesity, and not simply rely on BMI. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Public Library of Science | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Fatty Liver/complications* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Obesity, Abdominal/complications* | - |
dc.title | The relationship between visceral obesity and hepatic steatosis measured by controlled attenuation parameter. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Hye Won Lee | - |
dc.contributor.googleauthor | Kwang Joon Kim | - |
dc.contributor.googleauthor | Kyu Sik Jung | - |
dc.contributor.googleauthor | Young Eun Chon | - |
dc.contributor.googleauthor | Ji Hye Huh | - |
dc.contributor.googleauthor | Kyeong Hye Park | - |
dc.contributor.googleauthor | Jae Bock Chung | - |
dc.contributor.googleauthor | Chang Oh Kim | - |
dc.contributor.googleauthor | Kwang-Hyub Han | - |
dc.contributor.googleauthor | Jun Yong Park | - |
dc.identifier.doi | 10.1371/journal.pone.0187066 | - |
dc.contributor.localId | A00317 | - |
dc.contributor.localId | A01044 | - |
dc.contributor.localId | A01675 | - |
dc.contributor.localId | A03318 | - |
dc.contributor.localId | A03578 | - |
dc.contributor.localId | A03706 | - |
dc.contributor.localId | A04268 | - |
dc.relation.journalcode | J02540 | - |
dc.identifier.eissn | 1932-6203 | - |
dc.identifier.pmid | 29077769 | - |
dc.contributor.alternativeName | Kim, Kwang Joon | - |
dc.contributor.alternativeName | Kim, Chang Oh | - |
dc.contributor.alternativeName | Park, Jun Yong | - |
dc.contributor.alternativeName | Lee, Hye Won | - |
dc.contributor.alternativeName | Jung, Kyu Sik | - |
dc.contributor.alternativeName | Chung, Jae Bock | - |
dc.contributor.alternativeName | Han, Kwang Hyup | - |
dc.contributor.affiliatedAuthor | Kim, Kwang Joon | - |
dc.contributor.affiliatedAuthor | Kim, Chang Oh | - |
dc.contributor.affiliatedAuthor | Park, Jun Yong | - |
dc.contributor.affiliatedAuthor | Lee, Hye Won | - |
dc.contributor.affiliatedAuthor | Jung, Kyu Sik | - |
dc.contributor.affiliatedAuthor | Chung, Jae Bock | - |
dc.contributor.affiliatedAuthor | Han, Kwang Hyup | - |
dc.citation.volume | 12 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | e0187066 | - |
dc.identifier.bibliographicCitation | PLOS ONE, Vol.12(10) : e0187066, 2017 | - |
dc.identifier.rimsid | 61276 | - |
dc.type.rims | ART | - |
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