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A Successfully Treated Case of Recurrent Focal Segmental Glomerulosclerosis (FSGS) with Plasmapheresis and High dose Methylprednisolone Pulse Therapy

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dc.contributor.author신재일-
dc.contributor.author이금화-
dc.date.accessioned2018-07-20T08:34:58Z-
dc.date.available2018-07-20T08:34:58Z-
dc.date.issued2017-
dc.identifier.issn2384-0250-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/161302-
dc.description.abstractFocal segmental glomerulosclerosis (FSGS) in children, which is a kind of nephrotic syndrome showing steroid resistance, usually progresses to a substantial number of end stage renal disease (ESRD). Although the pathogenesis of primary FSGS is unclear, several recent studies have reported that FSGS is associated with circulating immune factors such as soluble urokinase-type plasminogen activator receptor (suPAR) or anti-CD40 autoantibody. We report a successfully treated case of a 19-year-old female patient who experienced a recurrence of primary FSGS. After the diagnosis of FSGS, the patient progressed to ESRD and received a kidney transplantation (KT). Three days later, recurrence was suspected through proteinuria and hypoalbuminemia. She has been performed plasmapheresis and high dose methylprednisolone pulse therapy and shown remission status without increasing proteinuria for four years after KT. In conclusion, strong immunosuppressive therapy may be helpful for a good prognosis of recurrent FSGS, suppressing several immunologic circulating factors related disease pathogenesis.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Society of Pediatric Nephrology-
dc.relation.isPartOfChildhood Kidney Diseases-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleA Successfully Treated Case of Recurrent Focal Segmental Glomerulosclerosis (FSGS) with Plasmapheresis and High dose Methylprednisolone Pulse Therapy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Pediatrics-
dc.contributor.googleauthorSun Mi Her-
dc.contributor.googleauthorKeum Hwa Lee-
dc.contributor.googleauthorJae Il Shin-
dc.identifier.doi10.3339/jkspn.2017.21.2.165-
dc.contributor.localIdA02142-
dc.contributor.localIdA04622-
dc.relation.journalcodeJ00524-
dc.identifier.eissn2384-0242-
dc.subject.keywordFocal segmental glomerulosclerosis-
dc.subject.keywordEnd stage renal disease-
dc.subject.keywordSoluble urokinase-type plasminogen activator receptor-
dc.subject.keywordAnti-CD40 autoantibody-
dc.contributor.alternativeNameShin, Jae Il-
dc.contributor.alternativeNameLee, Geum Hwa-
dc.contributor.affiliatedAuthorShin, Jae Il-
dc.contributor.affiliatedAuthorLee, Geum Hwa-
dc.citation.volume21-
dc.citation.number2-
dc.citation.startPage165-
dc.citation.endPage168-
dc.identifier.bibliographicCitationChildhood Kidney Diseases, Vol.21(2) : 165-168, 2017-
dc.identifier.rimsid61224-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers

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