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Impact of prosthesis-patient mismatch after mitral valve replacement in rheumatic population: Does mitral position prosthesis-patient mismatch really exist?

DC Field Value Language
dc.contributor.author유경종-
dc.contributor.author윤영남-
dc.contributor.author이삭-
dc.contributor.author이승현-
dc.contributor.author장병철-
dc.contributor.author주현철-
dc.date.accessioned2018-07-20T08:29:38Z-
dc.date.available2018-07-20T08:29:38Z-
dc.date.issued2017-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/161239-
dc.description.abstractBACKGROUND: Prosthesis-patient mismatch (PPM) is characterised by the effects of inadequate prosthesis size relative to body surface area (BSA).The purpose of this study was to determine the impact of PPM on late clinical outcomes after mitral valve replacement (MVR) in rheumatic population. METHODS: From 2000 to 2013, a total of 445 patients (mean age 54.2 ± 11.7 years) underwent isolated MVR (±tricuspid annuloplasty) for rheumatic disease were investigated. Effective orifice area (EOA) was determined by the continuity equation and PPM was defined as indexed EOA (EOA/BSA) ≤ 1.2 cm2/m2. Clinical and echocardiographic follow-up (mean follow up 8.7 ± 4.0 years) results were compared. RESULTS: 37% of patients (n = 165) had PPM. There were no significant differences in baseline and operative characteristics between patients with and without PPM except age and IEOA. A significant decrease in mean trans-valvular pressure gradient (MPG) over time following MVR, however the change of MPG showed no differences between groups (No PPM vs. PPM: 8.9 ± 4.7 mmHg → 3.6 ± 1.2 mmHg vs. 8.7 ± 4.5 mmHg → 3.8 ± 1.4 mmHg, p-value = 0.28). In all patients, there was a reduction of left atrium dimension (58.6 ± 12.0 mm → 53.2 ± 12.0 mm vs. 57.9 ± 8.9 mm → 52.2 ± 8.9 mm, p-value = 0.68) and left ventricular end diastolic diameter (49.9 ± 5.7 mm → 48.9 ± 5.7 mm vs. 49.7 ± 6.0 mm → 48.3 ± 5.0 mm, p = 0.24) without statistical significance. Freedom from TR progression rates at 3 and 5 years (99% vs.98%, 99% vs. 98%, p-value = 0.1), and overall survival rates at 3 and 5 years (97% vs. 96%, 94% vs. 94%, p-value = 0.7) were similar. CONCLUSION: This study shows that mitral PPM is not associated with atrial /ventricular remodeling and might not influence late clinical outcome including late TR progression, survival in rheumatic population.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherBioMed Central-
dc.relation.isPartOfJOURNAL OF CARDIOTHORACIC SURGERY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBalloon Valvuloplasty/adverse effects*-
dc.subject.MESHEchocardiography, Doppler-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHeart Valve Prosthesis/adverse effects*-
dc.subject.MESHHumans-
dc.subject.MESHIncidence-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMitral Valve/diagnostic imaging-
dc.subject.MESHMitral Valve/surgery*-
dc.subject.MESHMitral Valve Insufficiency/diagnosis-
dc.subject.MESHMitral Valve Insufficiency/etiology-
dc.subject.MESHMitral Valve Insufficiency/surgery*-
dc.subject.MESHPostoperative Complications/epidemiology*-
dc.subject.MESHProsthesis Design-
dc.subject.MESHProsthesis Failure-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRheumatic Heart Disease/complications*-
dc.subject.MESHRheumatic Heart Disease/epidemiology-
dc.subject.MESHSurvival Rate/trends-
dc.subject.MESHTime Factors-
dc.subject.MESHTreatment Outcome-
dc.titleImpact of prosthesis-patient mismatch after mitral valve replacement in rheumatic population: Does mitral position prosthesis-patient mismatch really exist?-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Thoracic & Cardiovascular Surgery-
dc.contributor.googleauthorSeung Hyun Lee-
dc.contributor.googleauthorByung Chul Chang-
dc.contributor.googleauthorYoung-Nam Youn-
dc.contributor.googleauthorHyun Chel Joo-
dc.contributor.googleauthorKyung-Jong Yoo-
dc.contributor.googleauthorSak Lee-
dc.identifier.doi10.1186/s13019-017-0653-x-
dc.contributor.localIdA02453-
dc.contributor.localIdA02576-
dc.contributor.localIdA02807-
dc.contributor.localIdA02935-
dc.contributor.localIdA03430-
dc.contributor.localIdA03960-
dc.relation.journalcodeJ01290-
dc.identifier.eissn1749-8090-
dc.identifier.pmid29017586-
dc.subject.keywordHeart valve prosthesis-
dc.subject.keywordHemodynamics-
dc.subject.keywordMitral valve-
dc.subject.keywordMortality-
dc.subject.keywordSurgery-
dc.subject.keywordValves-
dc.contributor.alternativeNameYoo, Kyung Jong-
dc.contributor.alternativeNameYoun, Young Nam-
dc.contributor.alternativeNameLee, Sak-
dc.contributor.alternativeNameLee, Seung Hyun-
dc.contributor.alternativeNameChang, Byung Chul-
dc.contributor.alternativeNameJoo, Hyun Chel-
dc.contributor.affiliatedAuthorYoo, Kyung Jong-
dc.contributor.affiliatedAuthorYoun, Young Nam-
dc.contributor.affiliatedAuthorLee, Sak-
dc.contributor.affiliatedAuthorLee, Seung Hyun-
dc.contributor.affiliatedAuthorChang, Byung Chul-
dc.contributor.affiliatedAuthorJoo, Hyun Chel-
dc.citation.volume12-
dc.citation.number1-
dc.citation.startPage88-
dc.identifier.bibliographicCitationJOURNAL OF CARDIOTHORACIC SURGERY, Vol.12(1) : 88, 2017-
dc.identifier.rimsid61161-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers

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