Cited 92 times in
Cancer Risk in the Early Stages of Inflammatory Bowel Disease in Korean Patients: A Nationwide Population-based Study
DC Field | Value | Language |
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dc.contributor.author | 김원호 | - |
dc.contributor.author | 박소희 | - |
dc.contributor.author | 천재희 | - |
dc.contributor.author | 한민경 | - |
dc.date.accessioned | 2018-07-20T08:25:38Z | - |
dc.date.available | 2018-07-20T08:25:38Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1873-9946 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/161178 | - |
dc.description.abstract | Background and Aims: The association between inflammatory bowel disease [IBD] and cancer remains poorly defined in Asian populations. Therefore, we conducted a nationwide population-based study to determine the cancer risk in Korean patients with IBD. Methods: Using the National Health Insurance claims data, we collected data on patients diagnosed with IBD (5595 Crohn's disease [CD] and 10 049 ulcerative colitis [UC]) from 2011 to 2014. Standardized incidence ratios [SIRs] of overall and site-specific cancers in IBD patients in comparison with the general population were calculated. Results: The overall cancer risk was higher in CD patients [SIR, 2.2; 95% confidence interval, 1.5-3.0 in men and 3.3; 2.4-4.5 in women] and UC patients [1.9; 1.6-2.3 in men and 1.9; 1.5-2.4 in women]. There were significantly increased risks for the following cancers: small bowel cancer [31.2; 3.8-112.8], colorectal cancer [CRC] [3.7; 1.6-7.2] and haematological cancer [4.0; 1.1-10.3] in men with CD; small bowel cancer [61.1; 7.4-220.6], CRC [4.7; 1.5-10.9], liver cancer [15.3; 5.6-33.2], pancreatic cancer [8.6; 1.0-31.0] and haematological cancer [11.0; 3.6-25.7] in women with CD; CRC [2.1; 1.3-3.3] and cancer of the prostate [3.5; 2.1-5.5], brain/central nervous system [6.1; 1.3-17.9] and thyroid [2.2; 1.1-3.9] in men with UC; and CRC [3.0; 1.5-5.3], cancer of the liver [4.4; 1.6-9.7] and cervix uteri [5.7; 2.4-11.1], and haematological cancer [3.5; 1.1-8.1] in women with UC. Women with CD had an increased risk of non-Hodgkin lymphoma [NHL] and leukaemia. Women with UC had an increased risk of NHL. Conclusions: Korean patients with IBD are at increased risk for overall, intestinal and haematological cancer. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Oxford University Press | - |
dc.relation.isPartOf | JOURNAL OF CROHNS & COLITIS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Cancer Risk in the Early Stages of Inflammatory Bowel Disease in Korean Patients: A Nationwide Population-based Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Yoon Suk Jung | - |
dc.contributor.googleauthor | Minkyung Han | - |
dc.contributor.googleauthor | Sohee Park | - |
dc.contributor.googleauthor | Won Ho Kim | - |
dc.contributor.googleauthor | Jae Hee Cheon | - |
dc.identifier.doi | 10.1093/ecco-jcc/jjx040 | - |
dc.contributor.localId | A00774 | - |
dc.contributor.localId | A01531 | - |
dc.contributor.localId | A04030 | - |
dc.contributor.localId | A05436 | - |
dc.relation.journalcode | J01359 | - |
dc.identifier.eissn | 1876-4479 | - |
dc.identifier.pmid | 28333358 | - |
dc.identifier.url | https://academic.oup.com/ecco-jcc/article/11/8/954/3072670 | - |
dc.subject.keyword | Crohn’s disease | - |
dc.subject.keyword | Korea | - |
dc.subject.keyword | Ulcerative colitis | - |
dc.subject.keyword | cancer | - |
dc.subject.keyword | population-based | - |
dc.contributor.alternativeName | Kim, Won Ho | - |
dc.contributor.alternativeName | Park, So Hee | - |
dc.contributor.alternativeName | Cheon, Jae Hee | - |
dc.contributor.alternativeName | Han, Minkyung | - |
dc.contributor.affiliatedAuthor | Kim, Won Ho | - |
dc.contributor.affiliatedAuthor | Park, So Hee | - |
dc.contributor.affiliatedAuthor | Cheon, Jae Hee | - |
dc.contributor.affiliatedAuthor | Han, Minkyung | - |
dc.citation.volume | 11 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 954 | - |
dc.citation.endPage | 962 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CROHNS & COLITIS, Vol.11(8) : 954-962, 2017 | - |
dc.identifier.rimsid | 61103 | - |
dc.type.rims | ART | - |
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