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Body mass index is inversely associated with mortality in patients with acute kidney injury undergoing continuous renal replacement therapy

DC FieldValueLanguage
dc.contributor.author강신욱-
dc.contributor.author기연경-
dc.contributor.author김주환-
dc.contributor.author김형래-
dc.contributor.author박서현-
dc.contributor.author박정탁-
dc.contributor.author서창환-
dc.contributor.author유태현-
dc.contributor.author윤창연-
dc.contributor.author윤해룡-
dc.contributor.author이미솔-
dc.contributor.author정수영-
dc.contributor.author지종현-
dc.contributor.author차민욱-
dc.contributor.author한승혁-
dc.date.accessioned2018-07-20T08:24:28Z-
dc.date.available2018-07-20T08:24:28Z-
dc.date.issued2017-
dc.identifier.issn2211-9132-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/161160-
dc.description.abstractBACKGROUND: Many epidemiologic studies have reported on the controversial concept of the obesity paradox. The presence of acute kidney injury (AKI) can accelerate energy-consuming processes, particularly in patients requiring continuous renal replacement therapy (CRRT). Thus, we aimed to investigate whether obesity can provide a survival benefit in this highly catabolic condition. METHODS: We conducted an observational study in 212 patients who had undergone CRRT owing to various causes of AKI between 2010 and 2014. The study end point was defined as death that occurred within 30 days after the initiation of CRRT. RESULTS: Patients were categorized into three groups according to tertiles of body mass index (BMI). During ≥30 days after the initiation of CRRT, 39 patients (57.4%) in the highest tertile died, as compared with 58 patients (78.4%) in the lowest tertile (P = 0.02). In a multivariable analysis adjusted for cofounding factors, the highest tertile of BMI was significantly associated with a decreased risk of death (hazard ratio [HR], 0.57; 95% confidence interval [CI], 0.37-0.87; P = 0.01). This significant association remained unaltered for 60-day (HR, 0.64; 95% CI, 0.43-0.94; P = 0.03) and 90-day mortality (HR, 0.66; 95% CI, 0.44-0.97; P = 0.03). CONCLUSION: This study showed that a higher BMI confer a survival benefit over a lower BMI in AKI patients undergoing CRRT.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherElsevier Korea-
dc.relation.isPartOfKIDNEY RESEARCH AND CLINICAL PRACTICE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleBody mass index is inversely associated with mortality in patients with acute kidney injury undergoing continuous renal replacement therapy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorHyoungnae Kim-
dc.contributor.googleauthorJoohwan Kim-
dc.contributor.googleauthorChanghwan Seo-
dc.contributor.googleauthorMisol Lee-
dc.contributor.googleauthorMin-Uk Cha-
dc.contributor.googleauthorSu-Young Jung-
dc.contributor.googleauthorJong Hyun Jhee-
dc.contributor.googleauthorSeohyun Park-
dc.contributor.googleauthorHae-Ryong Yun-
dc.contributor.googleauthorYoun Kyung Kee-
dc.contributor.googleauthorChang-Yun Yoon-
dc.contributor.googleauthorHyung Jung Oh-
dc.contributor.googleauthorJung Tak Park-
dc.contributor.googleauthorTae Ik Chang-
dc.contributor.googleauthorTae-Hyun Yoo-
dc.contributor.googleauthorShin-Wook Kang-
dc.contributor.googleauthorSeung Hyeok Han-
dc.identifier.doi10.23876/j.krcp.2017.36.1.39-
dc.contributor.localIdA00053-
dc.contributor.localIdA00276-
dc.contributor.localIdA05319-
dc.contributor.localIdA01147-
dc.contributor.localIdA01495-
dc.contributor.localIdA01654-
dc.contributor.localIdA04957-
dc.contributor.localIdA02526-
dc.contributor.localIdA02613-
dc.contributor.localIdA04617-
dc.contributor.localIdA02771-
dc.contributor.localIdA04667-
dc.contributor.localIdA03970-
dc.contributor.localIdA05046-
dc.contributor.localIdA04304-
dc.relation.journalcodeJ01942-
dc.identifier.eissn2211-9140-
dc.identifier.pmid28392996-
dc.subject.keywordAcute kidney injury-
dc.subject.keywordBody mass index-
dc.subject.keywordContinuous renal replacement therapy-
dc.subject.keywordMortality-
dc.subject.keywordObesity-
dc.contributor.alternativeNameKang, Shin Wook-
dc.contributor.alternativeNameKee, Youn Kyung-
dc.contributor.alternativeNameKim, Joohwan-
dc.contributor.alternativeNameKim, Hyoung Rae-
dc.contributor.alternativeNamePark, Seo Hyun-
dc.contributor.alternativeNamePark, Jung Tak-
dc.contributor.alternativeNameSeo, Changhwan-
dc.contributor.alternativeNameYoo, Tae Hyun-
dc.contributor.alternativeNameYoon, Chang Yun-
dc.contributor.alternativeNameYun, Hae Ryong-
dc.contributor.alternativeNameLee, Mi Sol-
dc.contributor.alternativeNameJung, Su Young-
dc.contributor.alternativeNameJhee, Jong Hyun-
dc.contributor.alternativeNameCha, Min Uk-
dc.contributor.alternativeNameHan, Seung Hyeok-
dc.contributor.affiliatedAuthorKang, Shin Wook-
dc.contributor.affiliatedAuthorKee, Youn Kyung-
dc.contributor.affiliatedAuthorKim, Joohwan-
dc.contributor.affiliatedAuthorKim, Hyoung Rae-
dc.contributor.affiliatedAuthorPark, Seo Hyun-
dc.contributor.affiliatedAuthorPark, Jung Tak-
dc.contributor.affiliatedAuthorSeo, Changhwan-
dc.contributor.affiliatedAuthorYoo, Tae Hyun-
dc.contributor.affiliatedAuthorYoon, Chang Yun-
dc.contributor.affiliatedAuthorYun, Hae Ryong-
dc.contributor.affiliatedAuthorLee, Mi Sol-
dc.contributor.affiliatedAuthorJung, Su Young-
dc.contributor.affiliatedAuthorJhee, Jong Hyun-
dc.contributor.affiliatedAuthorCha, Min Uk-
dc.contributor.affiliatedAuthorHan, Seung Hyeok-
dc.citation.volume36-
dc.citation.number1-
dc.citation.startPage39-
dc.citation.endPage47-
dc.identifier.bibliographicCitationKIDNEY RESEARCH AND CLINICAL PRACTICE, Vol.36(1) : 39-47, 2017-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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