205 301

Cited 8 times in

Gender Difference in the Prognostic Value of N-Terminal Pro-B Type Natriuretic Peptide in Patients With Heart Failure - A Report From the Korean Heart Failure Registry (KorHF)

DC Field Value Language
dc.contributor.author강석민-
dc.date.accessioned2018-07-20T08:24:09Z-
dc.date.available2018-07-20T08:24:09Z-
dc.date.issued2017-
dc.identifier.issn1346-9843-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/161152-
dc.description.abstractBACKGROUND: Very little data is available to evaluate the gender-specific role of N-terminal pro-B type natriuretic peptide (NT-proBNP). This study was performed to investigate whether there is a gender difference in the prognostic value of NT-proBNP in patients hospitalized for heart failure (HF).Methods and Results:A total of 2,280 patients hospitalized with HF (67.9±14.3 years, 50.9% women) from the nationwide registry database were analyzed. Composite events including all-cause mortality and HF readmission were assessed. During the mean follow-up period of 1,245±824 days, there were 1,067 cases of composite events (49.7%). NT-proBNP levels were significantly higher in patients with events than those without in both genders (P<0.001 for each). A higher NT-proBNP level was an independent predictor of events (highest vs. lowest tertile: hazard ratio [HR], 1.74; 95% confidence interval [CI], 1.25-2.43; P=0.001) in men, even after controlling for potential confounders. However, NT-proBNP was not associated with the occurrence of composite events in women in the same multivariable analysis (P>0.05). CONCLUSIONS: In patients with HF, the NT-proBNP level seems to be a more valuable marker in the prediction of long-term mortality and HF readmission in men than in women.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish, Japanese-
dc.publisherJapanese Circulation Society-
dc.relation.isPartOfCIRCULATION JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleGender Difference in the Prognostic Value of N-Terminal Pro-B Type Natriuretic Peptide in Patients With Heart Failure - A Report From the Korean Heart Failure Registry (KorHF)-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorHack-Lyoung Kim-
dc.contributor.googleauthorMyung-A Kim-
dc.contributor.googleauthorDong-Ju Choi-
dc.contributor.googleauthorSeongwoo Han-
dc.contributor.googleauthorEun-Seok Jeon-
dc.contributor.googleauthorMyeong-Chan Cho-
dc.contributor.googleauthorJae-Joong Kim-
dc.contributor.googleauthorByung-Su Yoo-
dc.contributor.googleauthorMi-Seung Shin-
dc.contributor.googleauthorIn-Whan Seong-
dc.contributor.googleauthorYoungkeun Ahn-
dc.contributor.googleauthorSeok-Min Kang-
dc.contributor.googleauthorYoung-Jo Kim-
dc.contributor.googleauthorHyung Seop Kim-
dc.contributor.googleauthorShung Chull Chae-
dc.contributor.googleauthorByung-Hee Oh-
dc.contributor.googleauthorMyoung-Mook Lee-
dc.contributor.googleauthorKyu-Hyung Ryu-
dc.identifier.doi10.1253/circj.CJ-16-1345-
dc.contributor.localIdA00037-
dc.relation.journalcodeJ00534-
dc.identifier.eissn1347-4820-
dc.identifier.pmid28442636-
dc.subject.keywordGender-
dc.subject.keywordHeart failure-
dc.subject.keywordN-terminal pro-B type natriuretic peptide-
dc.subject.keywordPrognosis-
dc.contributor.alternativeNameKang, Seok Min-
dc.contributor.affiliatedAuthorKang, Seok Min-
dc.citation.volume81-
dc.citation.number9-
dc.citation.startPage1329-
dc.citation.endPage1336-
dc.identifier.bibliographicCitationCIRCULATION JOURNAL, Vol.81(9) : 1329-1336, 2017-
dc.identifier.rimsid61078-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.