Cited 21 times in
Gender Difference in the Prognostic Value of N-Terminal Pro-B Type Natriuretic Peptide in Patients With Heart Failure - A Report From the Korean Heart Failure Registry (KorHF)
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강석민 | - |
dc.date.accessioned | 2018-07-20T08:24:09Z | - |
dc.date.available | 2018-07-20T08:24:09Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1346-9843 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/161152 | - |
dc.description.abstract | BACKGROUND: Very little data is available to evaluate the gender-specific role of N-terminal pro-B type natriuretic peptide (NT-proBNP). This study was performed to investigate whether there is a gender difference in the prognostic value of NT-proBNP in patients hospitalized for heart failure (HF).Methods and Results:A total of 2,280 patients hospitalized with HF (67.9±14.3 years, 50.9% women) from the nationwide registry database were analyzed. Composite events including all-cause mortality and HF readmission were assessed. During the mean follow-up period of 1,245±824 days, there were 1,067 cases of composite events (49.7%). NT-proBNP levels were significantly higher in patients with events than those without in both genders (P<0.001 for each). A higher NT-proBNP level was an independent predictor of events (highest vs. lowest tertile: hazard ratio [HR], 1.74; 95% confidence interval [CI], 1.25-2.43; P=0.001) in men, even after controlling for potential confounders. However, NT-proBNP was not associated with the occurrence of composite events in women in the same multivariable analysis (P>0.05). CONCLUSIONS: In patients with HF, the NT-proBNP level seems to be a more valuable marker in the prediction of long-term mortality and HF readmission in men than in women. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English, Japanese | - |
dc.publisher | Japanese Circulation Society | - |
dc.relation.isPartOf | CIRCULATION JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Gender Difference in the Prognostic Value of N-Terminal Pro-B Type Natriuretic Peptide in Patients With Heart Failure - A Report From the Korean Heart Failure Registry (KorHF) | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Hack-Lyoung Kim | - |
dc.contributor.googleauthor | Myung-A Kim | - |
dc.contributor.googleauthor | Dong-Ju Choi | - |
dc.contributor.googleauthor | Seongwoo Han | - |
dc.contributor.googleauthor | Eun-Seok Jeon | - |
dc.contributor.googleauthor | Myeong-Chan Cho | - |
dc.contributor.googleauthor | Jae-Joong Kim | - |
dc.contributor.googleauthor | Byung-Su Yoo | - |
dc.contributor.googleauthor | Mi-Seung Shin | - |
dc.contributor.googleauthor | In-Whan Seong | - |
dc.contributor.googleauthor | Youngkeun Ahn | - |
dc.contributor.googleauthor | Seok-Min Kang | - |
dc.contributor.googleauthor | Young-Jo Kim | - |
dc.contributor.googleauthor | Hyung Seop Kim | - |
dc.contributor.googleauthor | Shung Chull Chae | - |
dc.contributor.googleauthor | Byung-Hee Oh | - |
dc.contributor.googleauthor | Myoung-Mook Lee | - |
dc.contributor.googleauthor | Kyu-Hyung Ryu | - |
dc.identifier.doi | 10.1253/circj.CJ-16-1345 | - |
dc.contributor.localId | A00037 | - |
dc.relation.journalcode | J00534 | - |
dc.identifier.eissn | 1347-4820 | - |
dc.identifier.pmid | 28442636 | - |
dc.subject.keyword | Gender | - |
dc.subject.keyword | Heart failure | - |
dc.subject.keyword | N-terminal pro-B type natriuretic peptide | - |
dc.subject.keyword | Prognosis | - |
dc.contributor.alternativeName | Kang, Seok Min | - |
dc.contributor.affiliatedAuthor | Kang, Seok Min | - |
dc.citation.volume | 81 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1329 | - |
dc.citation.endPage | 1336 | - |
dc.identifier.bibliographicCitation | CIRCULATION JOURNAL, Vol.81(9) : 1329-1336, 2017 | - |
dc.identifier.rimsid | 61078 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.