Cited 3 times in
Effectiveness of Vildagliptin in Clinical Practice: Pooled Analysis of Three Korean Observational Studies (the VICTORY Study)
DC Field | Value | Language |
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dc.contributor.author | 이병완 | - |
dc.date.accessioned | 2018-07-20T08:19:57Z | - |
dc.date.available | 2018-07-20T08:19:57Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 2314-6745 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/161097 | - |
dc.description.abstract | The present observational study aimed to evaluate the clinical effectiveness of vildagliptin with metformin in Korean patients with type 2 diabetes mellitus (T2DM). Data were pooled from the vildagliptin postmarketing survey (PMS), the vildagliptin/metformin fixed drug combination (DC) PMS, and a retrospective observational study of vildagliptin/metformin (fixed DC or free DC). The effectiveness endpoint was the proportion of patients who achieved a glycemic target (HbA1c) of ≤7.0% at 24 weeks. In total, 4303 patients were included in the analysis; of these, 2087 patients were eligible. The mean patient age was 56.99 ± 11.25 years. Overall, 58.94% patients achieved an HbA1c target of ≤7.0% at 24 weeks. The glycemic target achievement rate was significantly greater in patients with baseline HbA1c < 7.5% versus ≥7.5% (84.64% versus 43.97%), receiving care at the hospital versus clinic (67.95% versus 52.33%), and receiving vildagliptin/metformin fixed DC versus free DC (70.69% versus 55.42%). Multivariate logistic regression analysis indicated that disease duration (P < 0.0001), baseline HbA1c (P < 0.0001), and DC type (P = 0.0103) had significant effects on drug effectiveness. Vildagliptin plus metformin appeared as an effective treatment option for patients with T2DM in clinical practice settings in Korea. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Hindawi Publishing Corporation | - |
dc.relation.isPartOf | JOURNAL OF DIABETES RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Effectiveness of Vildagliptin in Clinical Practice: Pooled Analysis of Three Korean Observational Studies (the VICTORY Study) | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Sunghwan Suh, 1 Sun Ok Song, 2 Jae Hyeon Kim, 3 Hyungjin Cho, 4 Woo Je Lee, 5 , * and Byung-Wan Lee 6 , * | - |
dc.identifier.doi | 10.1155/2017/5282343 | - |
dc.contributor.localId | A02796 | - |
dc.relation.journalcode | J01378 | - |
dc.identifier.eissn | 2314-6753 | - |
dc.identifier.pmid | 29057274 | - |
dc.contributor.alternativeName | Lee, Byung Wan | - |
dc.contributor.affiliatedAuthor | Lee, Byung Wan | - |
dc.citation.volume | 2017 | - |
dc.citation.startPage | 5282343 | - |
dc.identifier.bibliographicCitation | JOURNAL OF DIABETES RESEARCH, Vol.2017 : 5282343, 2017 | - |
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