Cited 44 times in
Outbreak of KPC-2-producing Enterobacteriaceae caused by clonal dissemination of Klebsiella pneumoniae ST307 carrying an IncX3-type plasmid harboring a truncated Tn4401a
DC Field | Value | Language |
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dc.contributor.author | 이경원 | - |
dc.contributor.author | 이혁민 | - |
dc.contributor.author | 정석훈 | - |
dc.date.accessioned | 2018-07-20T08:16:41Z | - |
dc.date.available | 2018-07-20T08:16:41Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0732-8893 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/161037 | - |
dc.description.abstract | Over a 5-month period between the end of June and the beginning of November in 2015, a KPC-producing Enterobacteriaceae outbreak occurred in a general hospital in Busan, South Korea, being associated with a total of 50 clinical isolates from 47 patients. Multilocus sequence typing and pulsed-field gel electrophoresis were carried out for strain typing and whole-genome sequencing was performed to characterize the plasmids. A clonal spread of K. pneumoniae sequence type 307 (ST307) carrying a self-transferable IncX3-type plasmid harboring blaKPC-2 was responsible for the outbreak. Sporadic emergence of K. pneumoniae ST697 carrying an IncFII-type plasmid and a ST11 isolate harboring a small plasmid devoid of any known origin of replication were observed to be associated with blaKPC-3, but no further dissemination of these strains was identified. The results indicated a healthcare-associated infection associated with a blaKPC-harboring plasmid dissemination and a clonal spread of KPC-producing Enterobacteriaceae. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier Biomedical | - |
dc.relation.isPartOf | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Bacterial Proteins/genetics | - |
dc.subject.MESH | Cross Infection/microbiology | - |
dc.subject.MESH | Disease Outbreaks | - |
dc.subject.MESH | Electrophoresis, Gel, Pulsed-Field/methods | - |
dc.subject.MESH | Enterobacteriaceae/genetics | - |
dc.subject.MESH | Enterobacteriaceae/isolation & purification* | - |
dc.subject.MESH | Enterobacteriaceae Infections/microbiology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Klebsiella Infections/microbiology* | - |
dc.subject.MESH | Klebsiella pneumoniae/genetics | - |
dc.subject.MESH | Klebsiella pneumoniae/isolation & purification* | - |
dc.subject.MESH | Microbial Sensitivity Tests/methods | - |
dc.subject.MESH | Molecular Epidemiology/methods | - |
dc.subject.MESH | Multilocus Sequence Typing/methods | - |
dc.subject.MESH | Plasmids/genetics* | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Sequence Analysis, DNA/methods | - |
dc.subject.MESH | beta-Lactamases/genetics* | - |
dc.title | Outbreak of KPC-2-producing Enterobacteriaceae caused by clonal dissemination of Klebsiella pneumoniae ST307 carrying an IncX3-type plasmid harboring a truncated Tn4401a | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Laboratory Medicine | - |
dc.contributor.googleauthor | Jung Ok Kim | - |
dc.contributor.googleauthor | Sae Am Song | - |
dc.contributor.googleauthor | Eun-Jeong Yoon | - |
dc.contributor.googleauthor | Jeong Hwan Shin | - |
dc.contributor.googleauthor | Hyukmin Lee | - |
dc.contributor.googleauthor | Seok Hoon Jeong | - |
dc.contributor.googleauthor | Kyungwon Lee | - |
dc.identifier.doi | 10.1016/j.diagmicrobio.2016.12.012 | - |
dc.contributor.localId | A02649 | - |
dc.contributor.localId | A03286 | - |
dc.contributor.localId | A03619 | - |
dc.relation.journalcode | J00731 | - |
dc.identifier.eissn | 1879-0070 | - |
dc.identifier.pmid | 28185686 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0732889316304308 | - |
dc.subject.keyword | Carbapenem resistance | - |
dc.subject.keyword | IncX3 | - |
dc.subject.keyword | Klebsiella pneumoniae | - |
dc.subject.keyword | ST307 | - |
dc.subject.keyword | Tn4401a | - |
dc.subject.keyword | bla(KPC) | - |
dc.contributor.alternativeName | Lee, Kyung Won | - |
dc.contributor.alternativeName | Lee, Hyuk Min | - |
dc.contributor.alternativeName | Jeong, Seok Hoon | - |
dc.contributor.affiliatedAuthor | Lee, Kyung Won | - |
dc.contributor.affiliatedAuthor | Lee, Hyuk Min | - |
dc.contributor.affiliatedAuthor | Jeong, Seok Hoon | - |
dc.citation.volume | 87 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 343 | - |
dc.citation.endPage | 348 | - |
dc.identifier.bibliographicCitation | DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, Vol.87(4) : 343-348, 2017 | - |
dc.identifier.rimsid | 60928 | - |
dc.type.rims | ART | - |
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