Cited 6 times in
Less Fibrotic Burden Differently Affects the Long-Term Outcomes of Hepatocellular Carcinoma after Curative Resection.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김경식 | - |
dc.contributor.author | 김도영 | - |
dc.contributor.author | 박영년 | - |
dc.contributor.author | 안상훈 | - |
dc.contributor.author | 이혜원 | - |
dc.contributor.author | 최기홍 | - |
dc.contributor.author | 최진섭 | - |
dc.contributor.author | 한광협 | - |
dc.date.accessioned | 2018-07-20T08:07:57Z | - |
dc.date.available | 2018-07-20T08:07:57Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0030-2414 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/160861 | - |
dc.description.abstract | BACKGROUND: The clinical features of hepatocellular carcinoma (HCC) differ in patients with and without cirrhosis. OBJECTIVE: We aimed to investigate the long-term outcomes of noncirrhotic HCC patients after curative resection. METHODS: We retrospectively examined 649 consecutive patients with HCC who underwent curative resection from 1996 to 2012; 387 (59.6%) were cirrhotic and 262 (40.4%) were noncirrhotic. RESULTS: The mean age was 54.7 years, and 511 (78.7%) of the study participants were men. The most common cause of HCC was hepatitis B virus (n = 419, 64.6%). Noncirrhotic tumors were larger and more advanced than cirrhotic tumors. However, the noncirrhotic group showed better disease-free survival (DFS) and overall survival (OS) after resection than the cirrhotic group (median 64.0 vs. 56.0 months for OS and 48.0 vs. 31.0 months for DFS, p < 0.05). The predictors for HCC recurrence were cirrhosis, tumor number, portal vein invasion, and major surgery. CONCLUSIONS: Noncirrhotic HCC showed better DFS and OS after resection than cirrhotic HCC, although noncirrhotic HCC presented more aggressively. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Karger | - |
dc.relation.isPartOf | ONCOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Carcinoma, Hepatocellular/mortality | - |
dc.subject.MESH | Carcinoma, Hepatocellular/pathology | - |
dc.subject.MESH | Carcinoma, Hepatocellular/surgery | - |
dc.subject.MESH | Disease-Free Survival | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hepatectomy/mortality | - |
dc.subject.MESH | Hepatectomy/statistics & numerical data | - |
dc.subject.MESH | Hepatitis B/complications | - |
dc.subject.MESH | Hepatitis B/mortality | - |
dc.subject.MESH | Hepatitis B/pathology | - |
dc.subject.MESH | Hepatitis C/complications | - |
dc.subject.MESH | Hepatitis C/mortality | - |
dc.subject.MESH | Hepatitis C/pathology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Liver Cirrhosis/mortality | - |
dc.subject.MESH | Liver Cirrhosis/pathology | - |
dc.subject.MESH | Liver Neoplasms/mortality | - |
dc.subject.MESH | Liver Neoplasms/pathology | - |
dc.subject.MESH | Liver Neoplasms/surgery | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Recurrence, Local/mortality | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Survival Analysis | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Less Fibrotic Burden Differently Affects the Long-Term Outcomes of Hepatocellular Carcinoma after Curative Resection. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Surgery | - |
dc.contributor.googleauthor | Lee H.W. | - |
dc.contributor.googleauthor | Choi G.H. | - |
dc.contributor.googleauthor | Kim D.Y. | - |
dc.contributor.googleauthor | Park Y.N. | - |
dc.contributor.googleauthor | Kim K.S. | - |
dc.contributor.googleauthor | Choi J.S. | - |
dc.contributor.googleauthor | Ahn S.H. | - |
dc.contributor.googleauthor | Han K.-H | - |
dc.identifier.doi | 10.1159/000477173 | - |
dc.contributor.localId | A00299 | - |
dc.contributor.localId | A00385 | - |
dc.contributor.localId | A01563 | - |
dc.contributor.localId | A02226 | - |
dc.contributor.localId | A03318 | - |
dc.contributor.localId | A04046 | - |
dc.contributor.localId | A04199 | - |
dc.contributor.localId | A04268 | - |
dc.relation.journalcode | J02416 | - |
dc.identifier.eissn | 1423-0232 | - |
dc.identifier.pmid | 28571030 | - |
dc.identifier.url | https://www.karger.com/Article/FullText/477173 | - |
dc.subject.keyword | Cirrhosis | - |
dc.subject.keyword | Hepatocellular carcinoma | - |
dc.subject.keyword | Surgical resection | - |
dc.contributor.alternativeName | Kim, Kyung Sik | - |
dc.contributor.alternativeName | Kim, Do Young | - |
dc.contributor.alternativeName | Park, Young Nyun | - |
dc.contributor.alternativeName | Ahn, Sang Hoon | - |
dc.contributor.alternativeName | Lee, Hye Won | - |
dc.contributor.alternativeName | Choi, Gi Hong | - |
dc.contributor.alternativeName | Choi, Jin Sub | - |
dc.contributor.alternativeName | Han, Kwang Hyup | - |
dc.contributor.affiliatedAuthor | Kim, Kyung Sik | - |
dc.contributor.affiliatedAuthor | Kim, Do Young | - |
dc.contributor.affiliatedAuthor | Park, Young Nyun | - |
dc.contributor.affiliatedAuthor | Ahn, Sang Hoon | - |
dc.contributor.affiliatedAuthor | Lee, Hye Won | - |
dc.contributor.affiliatedAuthor | Choi, Gi Hong | - |
dc.contributor.affiliatedAuthor | Choi, Jin Sub | - |
dc.contributor.affiliatedAuthor | Han, Kwang Hyup | - |
dc.citation.volume | 93 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 224 | - |
dc.citation.endPage | 232 | - |
dc.identifier.bibliographicCitation | ONCOLOGY, Vol.93(4) : 224-232, 2017 | - |
dc.identifier.rimsid | 60745 | - |
dc.type.rims | ART | - |
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