Cited 15 times in
Antibacterial activity and effect on gingival cells of microwave-pulsed non-thermal atmospheric pressure plasma in artificial saliva
DC Field | Value | Language |
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dc.contributor.author | 김경남 | - |
dc.contributor.author | 김광만 | - |
dc.date.accessioned | 2018-07-20T07:57:05Z | - |
dc.date.available | 2018-07-20T07:57:05Z | - |
dc.date.issued | 2017 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/160698 | - |
dc.description.abstract | Although various oral pathogens are inactivated by non-thermal atmospheric pressure plasma (NTAPP), the in vivo effects of NTAPP are poorly understood. The first aim of this study was to examine the antibacterial activity of microwave-pulsed NTAPP against Staphylococcus aureus in artificial saliva to mimic oral environmental conditions. The second aim was to determine the influence of microwave-pulsed NTAPP on human gingival fibroblasts (HGFs). The microwave-pulsed NTAPP reduced bacterial viability (as measured by colony forming units [CFU]) to a greater extent in artificial saliva than in saline. Extending the post-treatment incubation time increased bacterial inactivation in artificial saliva compared to saline. HGFs viability was unaffected by microwave-pulsed NTAPP for bacterial inactivation. Rather, HGFs proliferation increased after a 5-min microwave-pulsed NTAPP. Less tumor necrosis factor alpha was released by microwave-pulsed NTAPP-treated HGFs stimulated with lipopolysaccharide (LPS) than by untreated, LPS-stimulated HGFs; thus, plasma appeared to suppress the inflammatory response. Our study suggests that microwave-pulsed NTAPP may have stronger in vivo antibacterial activity than in vitro activity, and that microwave-pulsed NTAPP may have the additional advantage of suppressing gingival inflammatory responses. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Nature Publishing Group | - |
dc.relation.isPartOf | SCIENTIFIC REPORTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Antibacterial activity and effect on gingival cells of microwave-pulsed non-thermal atmospheric pressure plasma in artificial saliva | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry | - |
dc.contributor.department | Dept. of Dental Engineering | - |
dc.contributor.googleauthor | Sang-Hee Seo | - |
dc.contributor.googleauthor | Ihn Han | - |
dc.contributor.googleauthor | Han Seol Lee | - |
dc.contributor.googleauthor | Jin Joo Choi | - |
dc.contributor.googleauthor | Eun Ha Choi | - |
dc.contributor.googleauthor | Kyoung-Nam Kim | - |
dc.contributor.googleauthor | Gyungsoon Park | - |
dc.contributor.googleauthor | Kwang-Mahn Kim | - |
dc.identifier.doi | 10.1038/s41598-017-08725-0 | - |
dc.contributor.localId | A00292 | - |
dc.contributor.localId | A00312 | - |
dc.relation.journalcode | J02646 | - |
dc.identifier.eissn | 2045-2322 | - |
dc.identifier.pmid | 28827766 | - |
dc.contributor.alternativeName | Kim, Kyoung Nam | - |
dc.contributor.alternativeName | Kim, Kwang Mahn | - |
dc.contributor.affiliatedAuthor | Kim, Kyoung Nam | - |
dc.contributor.affiliatedAuthor | Kim, Kwang Mahn | - |
dc.citation.volume | 7 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 8395 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, Vol.7(1) : 8395, 2017 | - |
dc.identifier.rimsid | 42507 | - |
dc.type.rims | ART | - |
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