Cited 17 times in
Metabolic Complications among Korean Patients with HIV Infection: The Korea HIV/AIDS Cohort Study
DC Field | Value | Language |
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dc.contributor.author | 김준명 | - |
dc.contributor.author | 오동현 | - |
dc.contributor.author | 최준용 | - |
dc.date.accessioned | 2018-07-20T07:53:00Z | - |
dc.date.available | 2018-07-20T07:53:00Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/160625 | - |
dc.description.abstract | Currently, metabolic complications are the most common problem among human immunodeficiency virus (HIV)-infected patients, with a high incidence. However, there have been very few studies regarding metabolic abnormalities published in Asia, especially in Korea. This cross-sectional study was performed to investigate the prevalence of and risk factors for metabolic abnormalities in 1,096 HIV-infected patients of the Korea HIV/AIDS cohort study enrolled from 19 hospitals between 2006 and 2013. Data at entry to cohort were analyzed. As a result, the median age of the 1,096 enrolled subjects was 46 years, and most patients were men (92.8%). The metabolic profiles of the patients were as follows: median weight was 63.8 kg, median body mass index (BMI) was 22.2 kg/m², and 16.4% of the patients had a BMI over 25 kg/m². A total of 5.5% of the patients had abdominal obesity (waist/hip ratio ≥ 1 in men, ≥ 0.85 in women). Increased levels of fasting glucose, total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides were present in 10.4%, 6.0%, 5.5%, and 32.1% of the patients. Decreased high-density lipoprotein (HDL) cholesterol levels were observed in 44.2% of the patients. High systolic blood pressure was present in 14.3% of the patients. In multivariate analysis, high BMI and the use of protease inhibitors (PIs) were risk factors for dyslipidemia in HIV-infected patients. In conclusion, proper diagnosis and management should be offered for the prevalent metabolic complications of Korean HIV-infected patients. Further studies on risk factors for metabolic complications are needed. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | 대한의학회(The Korean Academy of Medical Sciences) | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Acquired Immunodeficiency Syndrome/complications | - |
dc.subject.MESH | Acquired Immunodeficiency Syndrome/diagnosis | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Anti-Retroviral Agents/therapeutic use | - |
dc.subject.MESH | Blood Glucose/analysis | - |
dc.subject.MESH | Body Mass Index | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Dyslipidemias/diagnosis | - |
dc.subject.MESH | Dyslipidemias/etiology | - |
dc.subject.MESH | HIV Infections/complications | - |
dc.subject.MESH | HIV Infections/diagnosis* | - |
dc.subject.MESH | HIV Infections/drug therapy | - |
dc.subject.MESH | Hospitals | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Metabolic Syndrome/diagnosis* | - |
dc.subject.MESH | Metabolic Syndrome/epidemiology | - |
dc.subject.MESH | Metabolic Syndrome/etiology | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Protease Inhibitors/therapeutic use | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Young Adult | - |
dc.title | Metabolic Complications among Korean Patients with HIV Infection: The Korea HIV/AIDS Cohort Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Internal Medicine | - |
dc.contributor.googleauthor | Dong Hyun Oh | - |
dc.contributor.googleauthor | Jin Young Ahn | - |
dc.contributor.googleauthor | Sang Il Kim | - |
dc.contributor.googleauthor | Min Ja Kim | - |
dc.contributor.googleauthor | Jun Hee Woo | - |
dc.contributor.googleauthor | Woo Joo Kim | - |
dc.contributor.googleauthor | Ji Hyeon Baek | - |
dc.contributor.googleauthor | Shin-Woo Kim | - |
dc.contributor.googleauthor | Bo Youl Choi | - |
dc.contributor.googleauthor | Mi Hwa Lee | - |
dc.contributor.googleauthor | Ju-yeon Choi | - |
dc.contributor.googleauthor | Myung Guk Han | - |
dc.contributor.googleauthor | Chun Kang | - |
dc.contributor.googleauthor | June Myung Kim | - |
dc.contributor.googleauthor | Jun Yong Choi | - |
dc.contributor.googleauthor | Korea HIV/AIDS Cohort Study | - |
dc.identifier.doi | 10.3346/jkms.2017.32.8.1268 | - |
dc.contributor.localId | A00953 | - |
dc.contributor.localId | A02361 | - |
dc.contributor.localId | A04191 | - |
dc.relation.journalcode | J01517 | - |
dc.identifier.eissn | 1598-6357 | - |
dc.identifier.pmid | 28665062 | - |
dc.subject.keyword | Dyslipidemia | - |
dc.subject.keyword | HIV Infection | - |
dc.subject.keyword | Metabolic Complication | - |
dc.subject.keyword | Protease Inhibitor | - |
dc.contributor.alternativeName | Kim, June Myung | - |
dc.contributor.alternativeName | Oh, Dong Hyun | - |
dc.contributor.alternativeName | Choi, Jun Yong | - |
dc.contributor.affiliatedAuthor | Kim, June Myung | - |
dc.contributor.affiliatedAuthor | Oh, Dong Hyun | - |
dc.contributor.affiliatedAuthor | Choi, Jun Yong | - |
dc.citation.volume | 32 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 1268 | - |
dc.citation.endPage | 1274 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.32(8) : 1268-1274, 2017 | - |
dc.identifier.rimsid | 40782 | - |
dc.type.rims | ART | - |
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