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Age-Based Causes and Clinical Characteristics of Immediate-Type Food Allergy in Korean Children

DC FieldValueLanguage
dc.contributor.author김경원-
dc.contributor.author김윤희-
dc.contributor.author손명현-
dc.date.accessioned2018-07-20T07:42:52Z-
dc.date.available2018-07-20T07:42:52Z-
dc.date.issued2017-
dc.identifier.issn2092-7355-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/160453-
dc.description.abstractPURPOSE: Age-based causes and clinical characteristics of immediate-type food allergy (FA) have not been sufficiently studied. Therefore, we investigated age-dependent clinical profiles of FA in Korean children through an extensive multicenter investigation. METHODS: Using a case report form developed by the authors, a retrospective medical record review was performed of patients (0-18 years old) diagnosed with immediate-type FA between September 2014 and August 2015 in 14 tertiary hospitals in Korea. RESULTS: A total of 1,353 children and adolescents, 93% younger than 7 years, were enrolled in the present study, and 1,661 cases of immediate-type FA were recorded in these patients. The 7 major causative foods were cow's milk (28.1%), hen's eggs (27.6%), wheat (7.9%), walnuts (7.3%), peanuts (5.3%), buckwheat (1.9%), and shrimps (1.9%). Categorizing the patients into 4 age groups revealed that the most common causative food was different for each age group: cow's milk (<2 years), walnuts (2-6 years), walnuts (7-12 years), and buckwheat (13-18 years). The onset time of symptoms was less than 10 minutes in 49%, between 10 and 30 minutes in 17%, and between 30 minutes and 2 hours in 34% of cases. Food-induced anaphylaxis was reported in 506 (30.5%) out of 1,661 cases, and the 7 major causes of food-induced anaphylaxis was cow's milk (27.5%), hen's eggs (21.9%), wheat (11.3%), walnuts (10.5%), peanuts (5.9%), buckwheat (4.2%), and pine nuts (3.0%). The proportion of anaphylaxis was highest in the patients allergic to buckwheat (67.7%), followed by those allergic to pine nuts (57.7%), walnuts (43.8%), wheat (43.5%), and peanuts (34.1%). CONCLUSIONS: The 5 major causative foods of immediate-type FA in Korean children were cow's milk, hen's eggs, wheat, walnuts, and peanuts. The distribution of causative foods was considerably distinctive according to different age groups. Anaphylaxis was reported in 30.5% of immediate-type FA cases.-
dc.description.statementOfResponsibilityopen-
dc.publisherKorean Academy of Pediatric Allergy and Respiratory Disease-
dc.relation.isPartOfAllergy Asthma & Immunology Research-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleAge-Based Causes and Clinical Characteristics of Immediate-Type Food Allergy in Korean Children-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Pediatrics-
dc.contributor.googleauthorKyunguk Jeong-
dc.contributor.googleauthorJihyun Kim-
dc.contributor.googleauthorKangmo Ahn-
dc.contributor.googleauthorSo-Yeon Lee-
dc.contributor.googleauthorTaek Ki Min-
dc.contributor.googleauthorBok Yang Pyun-
dc.contributor.googleauthorYoon Hee Kim-
dc.contributor.googleauthorKyung Won Kim-
dc.contributor.googleauthorMyung Hyun Sohn-
dc.contributor.googleauthorKyu-Earn Kim-
dc.contributor.googleauthorGwang Cheon Jang-
dc.contributor.googleauthorTae-Won Song-
dc.contributor.googleauthorJung Hee Kim-
dc.contributor.googleauthorYou Hoon Jeon-
dc.contributor.googleauthorYong Ju Lee-
dc.contributor.googleauthorYong Mean Park-
dc.contributor.googleauthorHye Yung Yum-
dc.contributor.googleauthorHyun Hee Kim-
dc.contributor.googleauthorWoo Kyung Kim-
dc.contributor.googleauthorSooyoung Lee-
dc.identifier.doi10.4168/aair.2017.9.5.423-
dc.contributor.localIdA00303-
dc.contributor.localIdA00799-
dc.contributor.localIdA01967-
dc.relation.journalcodeJ00064-
dc.identifier.eissn2092-7363-
dc.identifier.pmid28677356-
dc.subject.keywordFood hypersensitivity-
dc.subject.keywordIgE-mediated-
dc.subject.keywordadolescents-
dc.subject.keywordanaphylaxis-
dc.subject.keywordchildren-
dc.contributor.alternativeNameKim, Kyung Won-
dc.contributor.alternativeNameKim, Yoon Hee-
dc.contributor.alternativeNameSon, Myung Hyun-
dc.contributor.affiliatedAuthorKim, Kyung Won-
dc.contributor.affiliatedAuthorKim, Yoon Hee-
dc.contributor.affiliatedAuthorSon, Myung Hyun-
dc.citation.volume9-
dc.citation.number5-
dc.citation.startPage423-
dc.citation.endPage430-
dc.identifier.bibliographicCitationAllergy Asthma & Immunology Research, Vol.9(5) : 423-430, 2017-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers

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