0 144

Cited 0 times in

Differential Impact of Net Atrioventricular Compliance on Clinical Outcomes in Patients with Mitral Stenosis According to Cardiac Rhythm

DC FieldValueLanguage
dc.contributor.author심지영-
dc.contributor.author장혁재-
dc.contributor.author정남식-
dc.contributor.author조인정-
dc.contributor.author홍그루-
dc.date.accessioned2018-07-20T07:42:11Z-
dc.date.available2018-07-20T07:42:11Z-
dc.date.issued2017-
dc.identifier.issn0894-7317-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/160440-
dc.description.abstractBACKGROUND: Net atrioventricular compliance (Cn), a parameter for the net compliance of the left atrium and left ventricle, is known to be a useful predictor of outcomes in patients with mitral stenosis (MS). The present study aimed to evaluate whether the impact of Cn on symptom status and clinical outcomes, as well as its contribution toward systolic pulmonary artery pressure (SPAP), differed according to cardiac rhythm. METHODS: We retrospectively reviewed patients (N = 308) with rheumatic pure MS. Doppler-derived Cn was calculated using planimetered mitral valve area and E-wave downslope of transmitral flow. The primary endpoint was defined as a composite of all-cause death, percutaneous mitral valvotomy, surgical mitral valve replacement, admission for heart failure, and stroke. RESULTS: Overall, there were 178 patients (58%) with sinus rhythm (SR) and 130 patients (42%) with atrial fibrillation (AF). In multivariable linear regression analysis, there was a significant independent association between Cn and SPAP in patients with SR (P = .014), but not in those with AF (P = .112). During a median follow-up of 38 months, 130 patients (27%) experienced the study endpoint. In multivariable Cox regression, high Cn was associated with a more favorable prognosis in patients with SR (hazard ratio = 0.83; 95% CI, 0.69-0.99; P = .038). Conversely, high Cn was not found to offset the burden of adverse clinical outcomes in those with AF (hazard ratio = 1.18; 95% CI, 0.99-1.40; P = .071). CONCLUSIONS: Cn appears to be associated with SPAP and clinical outcomes in MS patients with SR. The predictive role of Cn in patients with AF requires further clarification.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherMosby-Year Book-
dc.relation.isPartOfJOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHCausality-
dc.subject.MESHComorbidity-
dc.subject.MESHDeath, Sudden, Cardiac/epidemiology-
dc.subject.MESHEchocardiography, Doppler*-
dc.subject.MESHFemale-
dc.subject.MESHHeart Atria/diagnostic imaging*-
dc.subject.MESHHeart Failure/diagnostic imaging-
dc.subject.MESHHeart Failure/mortality*-
dc.subject.MESHHeart Ventricles/diagnostic imaging*-
dc.subject.MESHHumans-
dc.subject.MESHImage Interpretation, Computer-Assisted*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMitral Valve Stenosis/diagnostic imaging*-
dc.subject.MESHMitral Valve Stenosis/mortality*-
dc.subject.MESHMitral Valve Stenosis/physiopathology-
dc.subject.MESHPrognosis-
dc.subject.MESHReproducibility of Results-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRisk Factors-
dc.subject.MESHSensitivity and Specificity-
dc.subject.MESHSurvival Rate-
dc.subject.MESHVascular Resistance-
dc.subject.MESHVascular Stiffness-
dc.titleDifferential Impact of Net Atrioventricular Compliance on Clinical Outcomes in Patients with Mitral Stenosis According to Cardiac Rhythm-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorIn-Jeong Cho-
dc.contributor.googleauthorHyuk-Jae Chang-
dc.contributor.googleauthorSoo Yeon Lee-
dc.contributor.googleauthorChi Young Shim-
dc.contributor.googleauthorGeu-Ru Hong-
dc.contributor.googleauthorNamsik Chung-
dc.identifier.doi10.1016/j.echo.2017.01.014-
dc.contributor.localIdA02213-
dc.contributor.localIdA03490-
dc.contributor.localIdA03585-
dc.contributor.localIdA03892-
dc.contributor.localIdA04386-
dc.relation.journalcodeJ01777-
dc.identifier.eissn1097-6795-
dc.identifier.pmid28283226-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0894731717300184-
dc.subject.keywordCardiac rhythm-
dc.subject.keywordCompliance-
dc.subject.keywordMitral valve stenosis-
dc.subject.keywordOutcome assessment-
dc.contributor.alternativeNameShim, Chi Young-
dc.contributor.alternativeNameChang, Hyuck Jae-
dc.contributor.alternativeNameChung, Nam Sik-
dc.contributor.alternativeNameCho, In Jeong-
dc.contributor.alternativeNameHong, Geu Ru-
dc.contributor.affiliatedAuthorShim, Chi Young-
dc.contributor.affiliatedAuthorChang, Hyuck Jae-
dc.contributor.affiliatedAuthorChung, Nam Sik-
dc.contributor.affiliatedAuthorCho, In Jeong-
dc.contributor.affiliatedAuthorHong, Geu Ru-
dc.citation.volume30-
dc.citation.number6-
dc.citation.startPage552-
dc.citation.endPage560-
dc.identifier.bibliographicCitationJOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, Vol.30(6) : 552-560, 2017-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.