350 619

Cited 16 times in

Comparison of the ImmunoCAP Assay and AdvanSure™ AlloScreen Advanced Multiplex Specific IgE Detection Assay.

DC Field Value Language
dc.contributor.author박경희-
dc.contributor.author박중원-
dc.contributor.author손영웅-
dc.contributor.author심다운-
dc.contributor.author이상철-
dc.contributor.author이재현-
dc.date.accessioned2018-07-20T07:39:48Z-
dc.date.available2018-07-20T07:39:48Z-
dc.date.issued2017-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/160396-
dc.description.abstractPURPOSE: The AdvanSure™ AlloScreen assay is an advanced multiplex test that allows for simultaneous detection of specific IgE (sIgE) against multiple allergens. For precise identification of causative allergens in allergic patients, we compared this new multiplex sIgE assay with the ImmunoCAP assay, which is currently the gold-standard method for sIgE detection. MATERIALS AND METHODS: Serum samples from 218 Korean allergic disease patients were used to compare the ImmunoCAP and AlloScreen assays with respect to the following 13 allergens: Dermatophagoides pteronyssinus, Dermatophagoides farinae, cat and dog dander, Alternaria, birch, oak, ragweed, mugwort, rye grass, and food allergens (egg white, cow's milk, peanuts). RESULTS: A total of 957 paired tests using the 13 allergens were compared. The total agreement ratio ranged from 0.74 (oak) to 0.97 (Alternaria). With respect to class association analyses, the gamma index ranged from 0.819 (rye grass) to 0.990 (Alternaria). The intra-class correlation coefficients for house dust mites, cat and dog dander, Alternaria, birch, ragweed, egg white, cow's milk, and peanut sIgE titers were >0.8. CONCLUSION: The AlloScreen and ImmunoCAP assays exhibited similar diagnostic performance. However, due to methodological differences between the two systems, careful interpretation of their results is needed in clinical applications.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAllergens/immunology-
dc.subject.MESHAnimals-
dc.subject.MESHDemography-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHImmunoassay/methods*-
dc.subject.MESHImmunoglobulin E/blood*-
dc.subject.MESHMale-
dc.subject.MESHSensitivity and Specificity-
dc.titleComparison of the ImmunoCAP Assay and AdvanSure™ AlloScreen Advanced Multiplex Specific IgE Detection Assay.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorKyung Hee Park-
dc.contributor.googleauthorJongsun Lee-
dc.contributor.googleauthorSang Chul Lee-
dc.contributor.googleauthorYoung Woong Son-
dc.contributor.googleauthorDa Woon Sim-
dc.contributor.googleauthorJae-Hyun Lee-
dc.contributor.googleauthorJung-Won Park-
dc.identifier.doi10.3349/ymj.2017.58.4.786-
dc.contributor.localIdA01427-
dc.contributor.localIdA01681-
dc.contributor.localIdA04588-
dc.contributor.localIdA04598-
dc.contributor.localIdA02831-
dc.contributor.localIdA03086-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid28540992-
dc.subject.keywordAllergens-
dc.subject.keywordimmunoassay-
dc.subject.keywordimmunoglobulin E-
dc.contributor.alternativeNamePark, Kyung Hee-
dc.contributor.alternativeNamePark, Jung Won-
dc.contributor.alternativeNameSon, Young Woong-
dc.contributor.alternativeNameSim, Da Woon-
dc.contributor.alternativeNameLee, Sang Chul-
dc.contributor.alternativeNameLee, Jae Hyun-
dc.contributor.affiliatedAuthorPark, Kyung Hee-
dc.contributor.affiliatedAuthorPark, Jung Won-
dc.contributor.affiliatedAuthorSon, Young Woong-
dc.contributor.affiliatedAuthorSim, Da Woon-
dc.contributor.affiliatedAuthorLee, Sang Chul-
dc.contributor.affiliatedAuthorLee, Jae Hyun-
dc.citation.volume58-
dc.citation.number4-
dc.citation.startPage786-
dc.citation.endPage792-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.58(4) : 786-792, 2017-
dc.identifier.rimsid44113-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.