Cited 7 times in
Investigating Serum Uric Acid as a Risk Factor in the Development of Delayed Renal Recovery in Living Kidney Donors.
DC Field | Value | Language |
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dc.contributor.author | 윤영은 | - |
dc.contributor.author | 이형호 | - |
dc.contributor.author | 한웅규 | - |
dc.date.accessioned | 2018-07-20T07:36:20Z | - |
dc.date.available | 2018-07-20T07:36:20Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0041-1345 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/160326 | - |
dc.description.abstract | BACKGROUND: Hyperuricemia has been associated with kidney disease and remains controversial with regard to its gender-specific differences and impact in living kidney donation. METHODS: Between 2006 and 2015, charts of live kidney donors who underwent nephrectomy and had a minimum follow-up of 1 year were reviewed. A total of 291 donors were included and divided based on gender-specific pre-donation serum uric acid (SUA) tertiles. Renal functional outcomes included were estimated glomerular filtration rate (eGFR) at 6-month and 1-year follow-up and percentage of donors with a 1-year eGFR <60 mL/min/1.72 m2. Logistic regression analysis was done. RESULTS: Mean SUA tertiles were 5.8 ± 1.1 mg/dL in males and 4.1 ± 1 mg/dL in females. Females in the highest tertile (SUA >4.5 mg/dL) had lower 6-month (59.9 ± 10.3 vs 66.9 ± 14.1 vs 67.3 ± 12.1; P = .018) and 1-year (60.8 ± 10.6 vs 67.6 ± 10.8 vs 67.8 ± 11.8; P = .021) eGFR and a higher percentage of donors with 1-year eGFR <60 mL/min/1.73 m2 (59.5% vs 31.6% vs 23%; P = .002) compared with donors in the lower SUA tertiles (≤4.5 mg/dL). In males, there were similar eGFRs among SUA tertiles at 6-month and 1-year follow-up. In multivariate analysis, SUA was shown to be a significant predictor of developing stage 3 CKD (eGFR <60 mL/min/1.72 m2), 1 year after donation in females but not in males. CONCLUSIONS: Predonation SUA level is associated with the development of delayed renal recovery (GFR <60 mL/min/1.72 m2) 1 year after donation in females but not in males. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier Science Inc. | - |
dc.relation.isPartOf | TRANSPLANTATION PROCEEDINGS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Glomerular Filtration Rate/physiology* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hyperuricemia/etiology* | - |
dc.subject.MESH | Kidney/physiopathology* | - |
dc.subject.MESH | Kidney Transplantation | - |
dc.subject.MESH | Living Donors* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Multivariate Analysis | - |
dc.subject.MESH | Nephrectomy/adverse effects* | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Tissue and Organ Procurement | - |
dc.subject.MESH | Uric Acid/blood | - |
dc.title | Investigating Serum Uric Acid as a Risk Factor in the Development of Delayed Renal Recovery in Living Kidney Donors. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Urology | - |
dc.contributor.googleauthor | R.C. Bravo | - |
dc.contributor.googleauthor | M.B. Gamo | - |
dc.contributor.googleauthor | H.H. Lee | - |
dc.contributor.googleauthor | Y.E. Yoon | - |
dc.contributor.googleauthor | W.K. Han | - |
dc.identifier.doi | 10.1016/j.transproceed.2017.03.034 | - |
dc.contributor.localId | A02581 | - |
dc.contributor.localId | A04647 | - |
dc.contributor.localId | A04308 | - |
dc.relation.journalcode | J02755 | - |
dc.identifier.eissn | 1873-2623 | - |
dc.identifier.pmid | 28583561 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S004113451730249X | - |
dc.contributor.alternativeName | Yoon, Young Eun | - |
dc.contributor.alternativeName | Lee, Hyung Ho | - |
dc.contributor.alternativeName | Han, Woong Kyu | - |
dc.contributor.affiliatedAuthor | Yoon, Young Eun | - |
dc.contributor.affiliatedAuthor | Lee, Hyung Ho | - |
dc.contributor.affiliatedAuthor | Han, Woong Kyu | - |
dc.citation.volume | 49 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 930 | - |
dc.citation.endPage | 934 | - |
dc.identifier.bibliographicCitation | TRANSPLANTATION PROCEEDINGS, Vol.49(5) : 930-934, 2017 | - |
dc.identifier.rimsid | 40987 | - |
dc.type.rims | ART | - |
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