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Factors Determining Aortic Valve Dysfunction in Korean Subjects With a Bicuspid Aortic Valve

DC FieldValueLanguage
dc.contributor.author김다래-
dc.contributor.author심지영-
dc.contributor.author정남식-
dc.contributor.author하종원-
dc.contributor.author홍그루-
dc.date.accessioned2018-07-20T07:30:30Z-
dc.date.available2018-07-20T07:30:30Z-
dc.date.issued2017-
dc.identifier.issn0002-9149-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/160235-
dc.description.abstractBicuspid aortic valve (BAV) disease has a male predominance of approximately 3:1 and shows diverse presentations about aortic valve dysfunction. This study aimed to find independent determinants for significant aortic stenosis (AS) or significant aortic regurgitation (AR) in adults with BAV. We retrospectively investigated the medical records of 1,073 subjects (773 men, mean age 55 ± 14 years) who were first diagnosed with BAV disease by transthoracic echocardiography. We excluded 52 subjects with both significant AS and significant AR. Of the remaining 1,021 subjects, 418 (41%) presented with significant AS, 249 (24%) showed significant AR, and the rest of the subjects were grouped into a normal functioning BAV (n = 354, 35%). BAV morphology was classified into the following 4 types according to position and pattern of raphe and cusps: (1) fusion of the right and left coronary cusps (type 1), (2) fusion of the right and noncoronary cusps (type 2), (3) fusion of the left and noncoronary (type 3), and (4) no raphe (type 0). Patients with significant AS were older, more likely to be women than men, and had a higher prevalence of type 0 BAV. Patients with significant AR were younger and were more likely to be men. In multivariate logistic regression analysis, women, older age, and type 0 or type 3 BAV were associated with significant AS. In contrast, men, hypertension, and chronic kidney disease were correlated with significant AR. Significant valve dysfunction in adults with first diagnosed BAV was closely associated with age, gender, and BAV morphology.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherExcerpta Medica-
dc.relation.isPartOfAMERICAN JOURNAL OF CARDIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAge Factors-
dc.subject.MESHAged-
dc.subject.MESHAortic Valve/abnormalities*-
dc.subject.MESHAortic Valve/diagnostic imaging*-
dc.subject.MESHAortic Valve/physiopathology-
dc.subject.MESHAortic Valve Insufficiency/epidemiology-
dc.subject.MESHAortic Valve Insufficiency/etiology-
dc.subject.MESHAortic Valve Insufficiency/physiopathology*-
dc.subject.MESHAortic Valve Stenosis/epidemiology-
dc.subject.MESHAortic Valve Stenosis/etiology-
dc.subject.MESHAortic Valve Stenosis/physiopathology*-
dc.subject.MESHEchocardiography, Doppler-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHeart Valve Diseases/complications*-
dc.subject.MESHHeart Valve Diseases/diagnosis-
dc.subject.MESHHeart Valve Diseases/epidemiology-
dc.subject.MESHHumans-
dc.subject.MESHIncidence-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Assessment*-
dc.subject.MESHRisk Factors-
dc.subject.MESHSex Factors-
dc.subject.MESHSurvival Rate/trends-
dc.titleFactors Determining Aortic Valve Dysfunction in Korean Subjects With a Bicuspid Aortic Valve-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Internal Medicine-
dc.contributor.googleauthorSoo Youn Lee-
dc.contributor.googleauthorChi Young Shim-
dc.contributor.googleauthorDarae Kim-
dc.contributor.googleauthorIksung Cho-
dc.contributor.googleauthorGeu-Ru Hong-
dc.contributor.googleauthorJong-Won Ha-
dc.contributor.googleauthorNamsik Chung-
dc.identifier.doi10.1016/j.amjcard.2017.03.038-
dc.contributor.localIdA00361-
dc.contributor.localIdA02213-
dc.contributor.localIdA03585-
dc.contributor.localIdA04257-
dc.contributor.localIdA04386-
dc.relation.journalcodeJ00071-
dc.identifier.eissn1879-1913-
dc.identifier.pmid28434646-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0002914917303624-
dc.contributor.alternativeNameKim, Da Rae-
dc.contributor.alternativeNameShim, Chi Young-
dc.contributor.alternativeNameChung, Nam Sik-
dc.contributor.alternativeNameHa, Jong Won-
dc.contributor.alternativeNameHong, Geu Ru-
dc.contributor.affiliatedAuthorKim, Da Rae-
dc.contributor.affiliatedAuthorShim, Chi Young-
dc.contributor.affiliatedAuthorChung, Nam Sik-
dc.contributor.affiliatedAuthorHa, Jong Won-
dc.contributor.affiliatedAuthorHong, Geu Ru-
dc.citation.volume119-
dc.citation.number12-
dc.citation.startPage2049-
dc.citation.endPage2055-
dc.identifier.bibliographicCitationAMERICAN JOURNAL OF CARDIOLOGY, Vol.119(12) : 2049-2055, 2017-
dc.identifier.rimsid38215-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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