63 71

Cited 5 times in

The clinical significance of serum ferritin in pediatric non-alcoholic Fatty liver disease

DC FieldValueLanguage
dc.contributor.author강윤구-
dc.contributor.author고홍-
dc.contributor.author김승-
dc.contributor.author나지훈-
dc.contributor.author박소원-
dc.date.accessioned2018-05-10T06:45:27Z-
dc.date.available2018-05-10T06:45:27Z-
dc.date.issued2014-
dc.identifier.issn2234-8646-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/158576-
dc.description.abstractPURPOSE: Non-alcoholic fatty liver disease (NAFLD) in children has become an important public health issue because of its high prevalence and severity. Several noninvasive methods for estimating NAFLD are under investigation. We aimed to evaluate the usefulness of serum ferritin as a biomarker of severity of pediatric NAFLD patients. METHODS: A total of 64 NAFLD patient were enrolled from Severance Children's Hospital from March 2010 to February 2013. Serum ferritin levels, liver related laboratory tests, liver magnetic resonance imaging (MRI) (2-dimensional [2D] proton density-fat fraction) and NAFLD severity markers were compared between obese group and overweight group. Correlation analyses were performed between serum ferritin and laboratory values including NAFLD severity markers. RESULTS: In obese group, serum ferritin, alanine aminotransferase (ALT), total bilirubin, international normalized ratio (INR), MRI 2D proton density-fat fraction, aspartate aminotransferase (AST) to platelet ratio index (APRI) and fibrosis-4 (FIB-4) (an index score calculated from platelet count, ALT, AST and age) were significantly higher than those of overweight group. NAFLD severity markers, APRI and FIB-4, and liver specific important laboratory values, AST, ALT, INR, cholesterol, triglyceride and low density lipoprotein show significant correlation with serum ferritin in NAFLD patients. CONCLUSION: Serum ferritin concentrations could be a candidate of useful severity marker in the pediatric NAFLD patients.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Society of Pediatric Gastroenterology, Hepatology and Nutrition-
dc.relation.isPartOfPediatric Gastroenterology, Hepatology & Nutrition-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleThe clinical significance of serum ferritin in pediatric non-alcoholic Fatty liver disease-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Pediatrics-
dc.contributor.googleauthorJi Hoon Na-
dc.contributor.googleauthorSo Won Park-
dc.contributor.googleauthorYunkoo Kang-
dc.contributor.googleauthorHong Koh-
dc.contributor.googleauthorSeung Kim-
dc.identifier.doi10.5223/pghn.2014.17.4.248-
dc.contributor.localIdA05213-
dc.contributor.localIdA00156-
dc.contributor.localIdA00651-
dc.contributor.localIdA05215-
dc.contributor.localIdA05216-
dc.relation.journalcodeJ02485-
dc.identifier.eissn2234-8840-
dc.identifier.pmid25587525-
dc.subject.keywordNon-alcoholic fatty liver disease-
dc.subject.keywordChild-
dc.subject.keywordFerritins-
dc.subject.keywordBiological markers-
dc.subject.keywordObesity-
dc.contributor.alternativeNameKang, Yunkoo-
dc.contributor.alternativeNameKoh, Hong-
dc.contributor.alternativeNameKim, Seung-
dc.contributor.alternativeNameNa, Ji Hoon-
dc.contributor.alternativeNamePark, So Won-
dc.contributor.affiliatedAuthorKang, Yunkoo-
dc.contributor.affiliatedAuthorKoh, Hong-
dc.contributor.affiliatedAuthorKim, Seung-
dc.contributor.affiliatedAuthorNa, Ji Hoon-
dc.contributor.affiliatedAuthorPark, So Won-
dc.citation.volume17-
dc.citation.number4-
dc.citation.startPage248-
dc.citation.endPage256-
dc.identifier.bibliographicCitationPediatric Gastroenterology, Hepatology & Nutrition, Vol.17(4) : 248-256, 2014-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.