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Two cases of chronic pancreatitis associated with anomalous pancreaticobiliary ductal union and SPINK1 mutation

DC FieldValueLanguage
dc.contributor.author고홍-
dc.date.accessioned2018-05-10T06:43:04Z-
dc.date.available2018-05-10T06:43:04Z-
dc.date.issued2013-
dc.identifier.issn1738-1061-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/158495-
dc.description.abstractChronic pancreatitis is a progressive inflammatory disease resulting from repeated episodes of acute pancreatitis that impair exocrine function and eventually produce endocrine insufficiency. Some causes of chronic pancreatitis appear to be associated with alterations in the serine-protease inhibitor, Kazal type 1 (SPINK1), cationic trypsinogen (PRSS1), and cystic fibrosis-transmembrane conductance regulator (CFTR) genes, or with structural disorders in the pancreaticobiliary ductal system, such as pancreatic divisum or anomalous pancreaticobiliary ductal union (APBDU). However, it is unusual to observe both genetic alteration and structural anomaly. Here, we report 2 cases with both APBDU and a mutation in the SPINK1 genes, and we discuss the implications of these findings in clinical practice.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean-
dc.publisher대한소아과학회-
dc.relation.isPartOfKorean Journal of Pediatrics-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleTwo cases of chronic pancreatitis associated with anomalous pancreaticobiliary ductal union and SPINK1 mutation-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Pediatrics-
dc.contributor.googleauthorEun Sam Rho-
dc.contributor.googleauthorEarl Kim-
dc.contributor.googleauthorHong Koh-
dc.contributor.googleauthorHan-Wook Yoo-
dc.contributor.googleauthorBeom Hee Lee-
dc.contributor.googleauthorGu-Hwan Kim-
dc.identifier.doi10.3345/kjp.2013.56.5.227-
dc.contributor.localIdA00156-
dc.relation.journalcodeJ02100-
dc.identifier.eissn2092-7258-
dc.identifier.pmid23741238-
dc.subject.keywordAnomalous pancreaticobiliary ductal union-
dc.subject.keywordChronic pancreatitis-
dc.subject.keywordKazal type 1-
dc.subject.keywordSerine protease inhibitor-
dc.contributor.alternativeNameKoh, Hong-
dc.contributor.affiliatedAuthorKoh, Hong-
dc.citation.volume56-
dc.citation.number5-
dc.citation.startPage227-
dc.citation.endPage230-
dc.identifier.bibliographicCitationKorean Journal of Pediatrics, Vol.56(5) : 227-230, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers

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