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Cited 18 times in

Cell Therapy for Diabetic Neuropathy Using Adult Stem or Progenitor Cells

DC FieldValueLanguage
dc.contributor.author윤영섭-
dc.date.accessioned2018-05-10T06:41:50Z-
dc.date.available2018-05-10T06:41:50Z-
dc.date.issued2013-
dc.identifier.issn2233-6079-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/158451-
dc.description.abstractDiabetic neuropathy (DN) is the most common and disabling complication of diabetes that may lead to foot ulcers and limb amputations. Despite widespread awareness of DN, the only effective treatments are glucose control and pain management. A growing body of evidence suggests that DN is characterized by reduction of vascularity in peripheral nerves and deficiency in neurotrophic and angiogenic factors. Previous studies have tried to introduce neurotrophic or angiogenic factors in the form of protein or gene for therapy, but the effect was not significant. Recent studies have shown that bone marrow (BM)-derived stem or progenitor cells have favorable effects on the repair of cardiovascular diseases. Since these BM-derived stem or progenitor cells contain various angiogenic and neurotrophic factors, these cells have been attempted for treating experimental DN, and turned out to be effective for reversing various manifestations of experimental DN. These evidences suggest that cell therapy, affecting both vascular and neural components, can represent a novel therapeutic option for treatment of clinical DN.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Diabetes Association-
dc.relation.isPartOfDIABETES & METABOLISM JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleCell Therapy for Diabetic Neuropathy Using Adult Stem or Progenitor Cells-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Life Science-
dc.contributor.googleauthorJi Woong Han-
dc.contributor.googleauthorMin Young Sin-
dc.contributor.googleauthorYoung-sup Yoon-
dc.identifier.doi10.4093/dmj.2013.37.2.91-
dc.contributor.localIdA02579-
dc.relation.journalcodeJ00720-
dc.identifier.eissn2233-6087-
dc.identifier.pmid23641349-
dc.subject.keywordDiabetic neuropathies-
dc.subject.keywordStem cells-
dc.subject.keywordTissue therapy-
dc.contributor.alternativeNameYoon, Young Sup-
dc.contributor.affiliatedAuthorYoon, Young Sup-
dc.citation.volume37-
dc.citation.number2-
dc.citation.startPage91-
dc.citation.endPage105-
dc.identifier.bibliographicCitationDIABETES & METABOLISM JOURNAL, Vol.37(2) : 91-105, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > BioMedical Science Institute (의생명과학부) > 1. Journal Papers

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