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폐구균 접종 후 비장절제술을 받은 만성면역혈소판감소자색반병 환아에서 발생한 폐렴사슬알균패혈증 1예

Other Titles
 Pneumococcal Sepsis 8 Years after Splenectomy for Chronic Immune Thrombocytopenia: A Case of Vaccinated 12-year-old Patient 
Authors
 이정표  ;  김효선  ;  한정우  ;  유철주 
Citation
 Clinical Pediatric Hematology-Oncology, Vol.20(1) : 62-65, 2013 
Journal Title
 Clinical Pediatric Hematology-Oncology 
ISSN
 2233-5250 
Issue Date
2013
Keywords
Immune thrombocytopenia ; Splenectomy ; Pneumococcal vaccine ; Sepsis
Abstract
Splenectomy is a safe and effective procedure in the refractory or chronic immune thrombocytopenia (ITP) patients. Overwhelming post-splenectomy infection (OPSI) is rare but fatal. The lifetime risk of post-splenectomy patients to develop an OPSI with encapsulated bacteria (Streptococcus pneumoniae, Haemophilus influenzae or Neisseria meningitidis) is about 1-5% and the mortality is reported more than 50% in 48 hours. Though vaccination against encapsulated bacteria cannot prevent all infection, vaccination is essential for the patients. We report a case of OPSI in a 12-year-old post-splenectomy boy who was vaccinated pneumococcal polysaccharide 7-valent against pneumococcus (Streptococcus pneumoniae) 2 months before splenectomy.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
김효선(Kim, Hyo Sun)
유철주(Lyu, Chuhl Joo) ORCID logo https://orcid.org/0000-0001-7124-7818
한정우(Han, Jung Woo) ORCID logo https://orcid.org/0000-0001-8936-1205
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/158400
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