Cited 25 times in
Treatment of secondary dystonia with a combined stereotactic procedure: long-term surgical outcomes
DC Field | Value | Language |
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dc.contributor.author | 장원석 | - |
dc.contributor.author | 장진우 | - |
dc.date.accessioned | 2018-05-10T06:33:44Z | - |
dc.date.available | 2018-05-10T06:33:44Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0001-6268 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/158204 | - |
dc.description.abstract | OBJECTIVE : There is some debate about the effects of pallidal deep brain stimulation (DBS) or lesioning on secondary dystonia. We applied a multimodal method to maximize the treatment effects of deep brain stimulation in patients with secondary dystonia. METHODS : Between March 2003 and January 2009, four patients underwent bilateral globus pallidus internus (GPi) DBS and six patients underwent bilateral GPi DBS plus unilateral thalamotomy for treatment of cerebral palsy (CP). Among the patients with secondary dystonia without CP, five were also treated by DBS. We classified patients with generalized secondary dystonia with cerebral palsy into group I and patients with focal dystonia without CP into group II. Clinical outcome assessments were based on Burke-Fahn-Marsden Dystonia Rating Scale movement and disability scores. Heath-related quality of life was assessed with a 36-item short-form general health survey questionnaire preoperatively and at the last follow-up. RESULTS : The movement and disability scores of group I-A had improved by 32.0% (P = 0.285) and 14.3% (P = 0.593), respectively, at the last follow-up compared with baseline. The movement and disability scores of group I-B had improved by 31.5% and 0.18% at the last follow-up compared with baseline, respectively. In comparison with patients in group I-A, patients in group I-B showed a significant improvement in movement scores for the contralateral arm (P = 0.042). Group II patients showed a marked improvement in movement and disability scores of 77.7% (P = 0.039) and 80.0% (P = 0.041), respectively. CONCLUSIONS : We demonstrated that DBS plus unilateral ventralis oralis thalamotomy for CP patients with fixed states in the upper extremities is useful not only to treat secondary dystonic movement but also to improve quality of life. In group II patients with post-traumatic dystonia and tardive dyskinesia, we achieved excellent clinical outcomes using a stereotactic procedure. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Springer | - |
dc.relation.isPartOf | ACTA NEUROCHIRURGICA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Cerebral Palsy/complications | - |
dc.subject.MESH | Cerebral Palsy/physiopathology* | - |
dc.subject.MESH | Cerebral Palsy/surgery | - |
dc.subject.MESH | Combined Modality Therapy/methods* | - |
dc.subject.MESH | Deep Brain Stimulation/methods* | - |
dc.subject.MESH | Dystonic Disorders/etiology | - |
dc.subject.MESH | Dystonic Disorders/physiopathology* | - |
dc.subject.MESH | Dystonic Disorders/therapy* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Longitudinal Studies | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neurosurgical Procedures/methods* | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Young Adult | - |
dc.title | Treatment of secondary dystonia with a combined stereotactic procedure: long-term surgical outcomes | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Neurosurgery | - |
dc.contributor.googleauthor | Joo Pyung Kim | - |
dc.contributor.googleauthor | Won Seok Chang | - |
dc.contributor.googleauthor | Jin Woo Chang | - |
dc.identifier.doi | 10.1007/s00701-011-1147-6 | - |
dc.contributor.localId | A03454 | - |
dc.contributor.localId | A03484 | - |
dc.relation.journalcode | J00018 | - |
dc.identifier.eissn | 0942-0940 | - |
dc.identifier.pmid | 21909834 | - |
dc.identifier.url | https://link.springer.com/article/10.1007/s00701-011-1147-6 | - |
dc.contributor.alternativeName | Chang, Won Seok | - |
dc.contributor.alternativeName | Chang, Jin Woo | - |
dc.contributor.affiliatedAuthor | Chang, Won Seok | - |
dc.contributor.affiliatedAuthor | Chang, Jin Woo | - |
dc.citation.volume | 153 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 2319 | - |
dc.citation.endPage | 2327 | - |
dc.identifier.bibliographicCitation | ACTA NEUROCHIRURGICA, Vol.153(12) : 2319-2327, 2011 | - |
dc.identifier.rimsid | 48958 | - |
dc.type.rims | ART | - |
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