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방사선 검사에서 뇌병변이 확인된 미숙아에서의 대근육 운동발달의 예후 인자

Other Titles
 Prognostic Indicators of Gross Motor Developmental Outcomes in Preterm Infants with Cerebral Insults as Detected by Neuroimaging 
Authors
 김승효  ;  김세희  ;  김헌민  ;  임병찬  ;  채종희  ;  김기중  ;  황용승  ;  최창원  ;  김병일  ;  황희 
Citation
 Journal of the Korean Child Neurology Society (대한소아신경학회지), Vol.18(2) : 254-263, 2010 
Journal Title
 Journal of the Korean Child Neurology Society (대한소아신경학회지) 
ISSN
 1226-6884 
Issue Date
2010
MeSH
Birth Weight ; Bronchopulmonary Dysplasia ; Cesarean Section ; Ductus Arteriosus, Patent ; Female ; Gestational Age ; Hemorrhage ; Humans ; Infant ; Infant, Newborn ; Infant, Premature ; Membranes ; Multivariate Analysis ; Neuroimaging ; Pregnancy ; Risk Factors ; Rupture ; Steroids
Keywords
Gestational age ; Premature rupture of membrane ; Development
Abstract
Purpose : To examine the developmental outcome of preterm infants with cerebral insults and to evaluate the prognostic indicators for gross motor development. Methods : Forty-eight preterm infants less than 37 weeks of gestation, who had been born at Seoul National University Bundang Hospital between March, 2004 and September, 2008 where the subjects of this. The infants' charts were reviewed to obtain data, including gestational age, birth weight, gender, 1/5 minute Apgar scores, neuroimaging findings, and others. Results : Of the 48 patients, 29 infants (60.4%) were put into a normal developmental group and 19 (39.6%) were put into developmental delay group. Univariate analysis of the two groups showed that P values less than 0.05 were observed with respect to gestational age, premature rupture of membrane (PROM), respiratory distress syndrome, bronchopulmonary dysplasia, and patent ductus arteriosus. PROM and antenatal steroid showed statistically significant differences on a multivariate analysis. The same analysis method was applied to preterm infants less than a corrected age of 32 weeks. Multivariate analysis suggested that PROM showed statistically significant differences. Also, 48 patients were analyzed with respect to neuroimage finding. Twenty-five infants (52.1%) were assigned to a germinal matrix hemorrhage (GMH) group and 23 infants (47.9%) were allocated to a non-GMH group. Cesarean section delivery showed statistically significant difference according to univariate analysis. Conclusion : In preterm infants with cerebral insults, PROM and antenatal steroids were independent risk factors for impaired gross motor development
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Se Hee(김세희) ORCID logo https://orcid.org/0000-0001-7773-1942
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/158121
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