Cited 8 times in
Effects of a 1:1 inspiratory to expiratory ratio on respiratory mechanics and oxygenation during one-lung ventilation in patients with low diffusion capacity of lung for carbon monoxide: a crossover study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김신형 | - |
dc.contributor.author | 오영준 | - |
dc.contributor.author | 최용선 | - |
dc.date.accessioned | 2018-03-26T17:11:56Z | - |
dc.date.available | 2018-03-26T17:11:56Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0952-8180 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/157329 | - |
dc.description.abstract | STUDY OBJECTIVE: To investigate the effects of a 1:1 inspiratory-to-expiratory (I:E) ventilation ratio on oxygenation and respiratory mechanics during one-lung ventilation (OLV) in patients with low diffusion capacity of lung for carbon monoxide (DLCO). DESIGN: Prospective, randomized, crossover study. SETTING: Operating room, university hospital. PATIENTS: Twenty-six patients with a preoperative DLCO less than 80% who were scheduled for lung lobectomy requiring OLV under general anesthesia. INTERVENTIONS: In the first group (n = 13), OLV was begun with a 1:1 I:E ratio, which was switched to a 1:2 I:E ratio after 30 minutes. In the second group (n = 13), the modes of ventilation were performed in the opposite order. Pressure-controlled ventilation with 5 cm H2O of positive end-expiratory pressure and a tidal volume of 5 to 8 mL/kg was applied during OLV. MEASUREMENTS: Arterial and central venous blood gas analyses were recorded and used to calculate intrapulmonary shunt fraction and physiologic dead space. These measurements were taken at 4 time points: 10 minutes after two-lung ventilation in the lateral decubitus position, 30 minutes after initiation of OLV, 30 minutes after switching the I:E ratio, and 10 minutes after two-lung ventilation was resumed. MAIN RESULTS: There was no difference in arterial oxygen tension during OLV between the 2 groups (P = .429). Arterial carbon dioxide tension and peak airway pressure were lower in the 1:1 group than in the 1:2 group (P = .003; P = .008). Physiologic dead space was also decreased in the 1:1 I:E ratio group (P = .003). Mean airway pressure and dynamic compliance were higher in the 1:1 group (P = .003; P = .007). CONCLUSIONS: Pressure-controlled ventilation with a 1:1 I:E ventilation ratio did not improve oxygenation in patients with low DLCO during OLV compared with a 1:2 I:E ventilation ratio. However, it did provide benefits in terms of respiratory mechanics and increased the efficiency of alveolar ventilation during OLV. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL ANESTHESIA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Carbon Monoxide/metabolism* | - |
dc.subject.MESH | Cross-Over Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Lung/metabolism* | - |
dc.subject.MESH | Lung/surgery | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | One-Lung Ventilation/methods* | - |
dc.subject.MESH | Oxygen Inhalation Therapy/methods* | - |
dc.subject.MESH | Positive-Pressure Respiration | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Pulmonary Diffusing Capacity* | - |
dc.subject.MESH | Respiratory Dead Space | - |
dc.subject.MESH | Respiratory Function Tests | - |
dc.subject.MESH | Respiratory Mechanics* | - |
dc.subject.MESH | Tidal Volume | - |
dc.subject.MESH | Young Adult | - |
dc.title | Effects of a 1:1 inspiratory to expiratory ratio on respiratory mechanics and oxygenation during one-lung ventilation in patients with low diffusion capacity of lung for carbon monoxide: a crossover study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine | - |
dc.contributor.googleauthor | Kyuho Lee | - |
dc.contributor.googleauthor | Young Jun Oh | - |
dc.contributor.googleauthor | Yong Seon Choi | - |
dc.contributor.googleauthor | Shin Hyung Kim | - |
dc.identifier.doi | 10.1016/j.jclinane.2015.06.012 | - |
dc.contributor.localId | A00676 | - |
dc.contributor.localId | A02389 | - |
dc.contributor.localId | A04119 | - |
dc.relation.journalcode | J01315 | - |
dc.identifier.eissn | 1873-4529 | - |
dc.identifier.pmid | 26263797 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S095281801500197X | - |
dc.subject.keyword | One-lung ventilation | - |
dc.subject.keyword | inspiratory-expiratory ratio | - |
dc.subject.keyword | oxygenation | - |
dc.subject.keyword | respiratory mechanics | - |
dc.contributor.alternativeName | Kim, Shin Hyung | - |
dc.contributor.alternativeName | Oh, Young Jun | - |
dc.contributor.alternativeName | Choi, Yong Seon | - |
dc.contributor.affiliatedAuthor | Kim, Shin Hyung | - |
dc.contributor.affiliatedAuthor | Oh, Young Jun | - |
dc.contributor.affiliatedAuthor | Choi, Yong Seon | - |
dc.citation.volume | 27 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 445 | - |
dc.citation.endPage | 450 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL ANESTHESIA, Vol.27(6) : 445-450, 2015 | - |
dc.identifier.rimsid | 42362 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.