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자궁경부암 선별검사로서 인유두종 바이러스 유전자형 검사의 경제성 평가
DC Field | Value | Language |
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dc.contributor.author | 김영태 | - |
dc.date.accessioned | 2018-03-26T17:04:46Z | - |
dc.date.available | 2018-03-26T17:04:46Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 2288-5811 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/157153 | - |
dc.description.abstract | Objectives: The aim of this study was to evaluate the cost-effectiveness of cervical cancer screening with a human papillomavirus (HPV) 16/18 genotyping test in Korea. Methods: We compared seven strategies with a Markov cohort model: 1) cytology with reflex HPV testing for atypical squamous cells of undetermined significance (ASC-US) (‘cytology’) (routine screening interval 1 year), 2–4) HPV with 16/18 genotyping with liquid-based cytology triage co-testing (‘co-testing’) (routine screening interval 1, 2, 3 year), and 5–7) HPV with 16/18 genotyping and reflex cytology (ASC-US threshold) (‘HPV with genotyping’) (routine screening interval 1, 2, 3 year). Screening start age was 30-year-old and screening was performed over 40 years. Screening sensitivity and specificity values for cervical intraepithelial neoplasia 3 were obtained from ‘Addressing THE Need for Advanced HPV Diagnostics,’ trial. Screening costs and cancer treatment costs were calculated from a payer’s perspective in 2012. Costs and quality adjusted life-years (QALYs) were discounted at 5% annually. Results: Applying a KRW ₩20–30 million/QALY threshold, ‘co-testing’ with 1 year interval and “HPV with genotyping” with 1 year interval were not cost effective, but ‘co-testing’ with 2, 3 year interval and “HPV with genotyping” with 2, 3 year interval were cost effective versus ‘cytology’ with 1 year. Conclusion: Compared with the existing ‘cytology’ with 1 year, HPV 16/18 genotyping with 2, 3 year interval can be cost effective. Especially, ‘co-testing’ with 2 year interval was the most cost-effectiveness strategy. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | Korean, English | - |
dc.publisher | Korean Association for Health Technology Assessment | - |
dc.relation.isPartOf | Journal of Health Technology Assessment (보건의료기술평가) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 자궁경부암 선별검사로서 인유두종 바이러스 유전자형 검사의 경제성 평가 | - |
dc.title.alternative | Cost Effectiveness of Human Papillomavirus 16/18 Genotyping in Cervical Cancer Screening | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Obstetrics & Gynecology | - |
dc.contributor.googleauthor | 최승미 | - |
dc.contributor.googleauthor | 주웅 | - |
dc.contributor.googleauthor | Joice Huang | - |
dc.contributor.googleauthor | 이재관 | - |
dc.contributor.googleauthor | 김태진 | - |
dc.contributor.googleauthor | 김병기 | - |
dc.contributor.googleauthor | 김승철 | - |
dc.contributor.googleauthor | 김영태 | - |
dc.contributor.googleauthor | 남계현 | - |
dc.contributor.googleauthor | 김수녕 | - |
dc.contributor.googleauthor | 송용상 | - |
dc.contributor.googleauthor | 오윤환 | - |
dc.contributor.googleauthor | 박주연 | - |
dc.contributor.googleauthor | 배덕수 | - |
dc.contributor.localId | A00729 | - |
dc.relation.journalcode | J01434 | - |
dc.subject.keyword | Cost-effectiveness | - |
dc.subject.keyword | Human papillomavirus 16/18 genotyping | - |
dc.subject.keyword | Cervical cancer screening | - |
dc.contributor.alternativeName | Kim, Young Tae | - |
dc.contributor.affiliatedAuthor | Kim, Young Tae | - |
dc.citation.volume | 3 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 107 | - |
dc.citation.endPage | 114 | - |
dc.identifier.bibliographicCitation | Journal of Health Technology Assessment (보건의료기술평가), Vol.3(2) : 107-114, 2015 | - |
dc.identifier.rimsid | 41716 | - |
dc.type.rims | ART | - |
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