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Nonvisible tumors on multiparametric magnetic resonance imaging does not predict low-risk prostate cancer

DC Field Value Language
dc.contributor.author구교철-
dc.contributor.author이동훈-
dc.contributor.author이승환-
dc.contributor.author정병하-
dc.date.accessioned2018-03-26T17:03:29Z-
dc.date.available2018-03-26T17:03:29Z-
dc.date.issued2015-
dc.identifier.issn2287-8882-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/157124-
dc.description.abstractPURPOSE: To determine whether multiparametric MRI could help predict the diagnosis of low-risk prostate cancer (PCA). METHODS: We retrospectively analyzed consecutive 623 patients with PCA who underwent multiparametric MRI before radical prostatectomy(RP). High-resolution T1- and T2-weighted, diffusion-weighted, and dynamic precontrast and postcontrast image sequences were obtained for each patient. Of the 623 patients, 177(28.4%) exhibited non visible tumors on MRI of clinical stage T1c. The imaging results were compared with the pathological findings with respect to both stage and Gleason scores (GS). RESULTS: Of the 177 prostatectomy patients with non visible tumors on MRI, pathological findings resulted in the upgrading of 49(27.7%) patients to a sum of GS 7 or more. 101(57.1%) patients exhibited tumor volumes greater than 0.5cc. The biochemical recurrence rate was significantly higher in the pathological upgraded group compared with the nonupgraded group after a mean follow-up time of 29 months. In the multiple logistic analysis, non visible tumor on MRI was not a significant predictor of low-risk PCA. CONCLUSIONS: Even though cancer foci were not visualized by postbiopsy MRI, the pathological tumor volumes and extent of GS upgrading were relatively high. Therefore, nonvisible tumors by multiparametric MRI do not appear to be predictive of low-risk PCA.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherAsian Pacific Prostate Society-
dc.relation.isPartOfPROSTATE INTERNATIONAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleNonvisible tumors on multiparametric magnetic resonance imaging does not predict low-risk prostate cancer-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Urology-
dc.contributor.googleauthorSeung Hwan Lee-
dc.contributor.googleauthorKyo Chul Koo-
dc.contributor.googleauthorDong Hoon Lee-
dc.contributor.googleauthorByung Ha Chung-
dc.identifier.doi10.1016/j.prnil.2015.09.005-
dc.contributor.localIdA00188-
dc.contributor.localIdA02742-
dc.contributor.localIdA02938-
dc.contributor.localIdA03607-
dc.relation.journalcodeJ02559-
dc.identifier.eissn2287-903X-
dc.identifier.pmid26779459-
dc.subject.keywordActive surveillance-
dc.subject.keywordLow risk-
dc.subject.keywordMagnetic resonance imaging-
dc.subject.keywordProstate cancer-
dc.contributor.alternativeNameKoo, Kyo Chul-
dc.contributor.alternativeNameLee, Dong Hoon-
dc.contributor.alternativeNameLee, Seung Hwan-
dc.contributor.alternativeNameChung, Byung Ha-
dc.contributor.affiliatedAuthorKoo, Kyo Chul-
dc.contributor.affiliatedAuthorLee, Dong Hoon-
dc.contributor.affiliatedAuthorLee, Seung Hwan-
dc.contributor.affiliatedAuthorChung, Byung Ha-
dc.citation.volume3-
dc.citation.number4-
dc.citation.startPage127-
dc.citation.endPage131-
dc.identifier.bibliographicCitationPROSTATE INTERNATIONAL, Vol.3(4) : 127-131, 2015-
dc.identifier.rimsid41687-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers

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