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Food allergen sensitization in young children with typical signs and symptoms of immediate-type food allergies: a comparison between monosensitized and polysensitized children

DC FieldValueLanguage
dc.contributor.author김규언-
dc.date.accessioned2018-03-26T16:46:29Z-
dc.date.available2018-03-26T16:46:29Z-
dc.date.issued2015-
dc.identifier.issn1738-1061-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/156805-
dc.description.abstractPURPOSE: The clinical interpretation of children sensitized to allergens is challenging, particularly in children with food allergies. We aimed to examine clinical differences between children with monosensitization and those with polysensitization to common food allergens and to determine risk factors for polysensitization in young children <10 years of age with immediate-type food allergies. METHODS: The study included children <10 years of age with signs and symptoms indicative of immediate-type food allergies. Serum total IgE level was measured, and ImmunoCAP analysis for food allergens was performed. RESULTS: The mean age of the study subjects was 1.6±1.6 years (75 boys and 51 girls). Thirty-eight children (30.2%) were monosensitized and 88 children (69.8%) were polysensitized. Multivariate logistic regression analysis showed that the development of polysensitization to common food allergens was positively associated with a parental history of allergic rhinitis (adjusted odds ratio [aOR], 6.28; 95% confidence interval [CI], 1.78-22.13; P=0.004), season of birth (summer/fall) (aOR, 3.10; 95% CI, 1.10-8.79; P=0.033), and exclusive breastfeeding in the first 6 months of age (aOR, 3.51; 95% CI, 1.20-10.25; P=0.022). CONCLUSION: We found significant clinical differences between children with monosensitization and those with polysensitization to common food allergens and identified risk factors for the development of polysensitization in young children with immediate-type food allergies. Clinicians should consider these clinical risk factors when evaluating, counseling, treating, and monitoring young children with food allergies.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean-
dc.publisher대한소아과학회-
dc.relation.isPartOfKorean Journal of Pediatrics-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleFood allergen sensitization in young children with typical signs and symptoms of immediate-type food allergies: a comparison between monosensitized and polysensitized children-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Pediatrics-
dc.contributor.googleauthorNa Yeon Kim-
dc.contributor.googleauthorGa Ram Kim-
dc.contributor.googleauthorJoon Hwan Kim-
dc.contributor.googleauthorJi Hyeon Baek-
dc.contributor.googleauthorJung Won Yoon-
dc.contributor.googleauthorHye Mi Jee-
dc.contributor.googleauthorHye Sung Baek-
dc.contributor.googleauthorYong Ho Jung-
dc.contributor.googleauthorSun Hee Choi-
dc.contributor.googleauthorKi Eun Kim-
dc.contributor.googleauthorYoun Ho Shin-
dc.contributor.googleauthorHye Yung Yum-
dc.contributor.googleauthorMan Yong Han-
dc.contributor.googleauthorKyu-Earn Kim-
dc.identifier.doi10.3345/kjp.2015.58.9.330-
dc.contributor.localIdA00327-
dc.relation.journalcodeJ02100-
dc.identifier.eissn2092-7258-
dc.identifier.pmid26512258-
dc.subject.keywordChild-
dc.subject.keywordFood hypersensitivity-
dc.subject.keywordSensitization-
dc.contributor.alternativeNameKim, Kyu Earn-
dc.contributor.affiliatedAuthorKim, Kyu Earn-
dc.citation.volume58-
dc.citation.number9-
dc.citation.startPage330-
dc.citation.endPage335-
dc.identifier.bibliographicCitationKorean Journal of Pediatrics, Vol.58(9) : 330-335, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers

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