152 337

Cited 25 times in

Specific Immunotherapy in Atopic Dermatitis

DC Field Value Language
dc.contributor.author박창욱-
dc.contributor.author이광훈-
dc.contributor.author이정수-
dc.date.accessioned2018-03-26T16:46:10Z-
dc.date.available2018-03-26T16:46:10Z-
dc.date.issued2015-
dc.identifier.issn2092-7355-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/156799-
dc.description.abstractAllergen specific immunotherapy (SIT) using house dust mite (HDM) extracts has been performed mainly with patients of asthma and allergic rhinitis. In the meanwhile, there has been a long debate on the efficacy of SIT in atopic dermatitis (AD) with only a few double-blind placebo-controlled trials. However, several randomized controlled trials of SIT in AD revealed significant improvement of clinical symptoms and also, positive result was shown by a following meta-analysis study of these trials. In order to predict and evaluate the treatment outcome, finding a biomarker that can predict treatment responses and treatment end-points is critical but it is very challenging at the same time due to the complexity of causes and mechanisms of AD. Other considerations including standardization of the easiest and safest treatment protocol and optimizing the treatment preparations should be studied as well. This review summarizes the basics of SIT in AD including the brief mechanisms, treatment methods and schedules, and also highlights the clinical efficacy of SIT in AD along with mild, controllable adverse reactions. Immunologic effects and studies of various biomarkers are also introduced and finally, future considerations with upcoming studies on SIT were discussed.-
dc.description.statementOfResponsibilityopen-
dc.publisherKorean Academy of Pediatric Allergy and Respiratory Disease-
dc.relation.isPartOfALLERGY ASTHMA & IMMUNOLOGY RESEARCH-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleSpecific Immunotherapy in Atopic Dermatitis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Dermatology-
dc.contributor.googleauthorJungsoo Lee-
dc.contributor.googleauthorChang Ook Park-
dc.contributor.googleauthorKwang Hoon Lee-
dc.identifier.doi10.4168/aair.2015.7.3.221-
dc.contributor.localIdA01716-
dc.contributor.localIdA02674-
dc.contributor.localIdA04637-
dc.relation.journalcodeJ00064-
dc.identifier.eissn2092-7363-
dc.identifier.pmid25749758-
dc.subject.keywordSpecific immunotherapy-
dc.subject.keywordatopic dermatitis-
dc.subject.keywordbiomarker-
dc.subject.keywordclinical efficacy-
dc.subject.keywordsubcutaneous immunotherapy-
dc.contributor.alternativeNamePark, Chang Ook-
dc.contributor.alternativeNameLee, Kwang Hoon-
dc.contributor.alternativeNameLee, Jungsoo-
dc.contributor.affiliatedAuthorPark, Chang Ook-
dc.contributor.affiliatedAuthorLee, Kwang Hoon-
dc.contributor.affiliatedAuthorLee, Jungsoo-
dc.citation.volume7-
dc.citation.number3-
dc.citation.startPage221-
dc.citation.endPage229-
dc.identifier.bibliographicCitationALLERGY ASTHMA & IMMUNOLOGY RESEARCH, Vol.7(3) : 221-229, 2015-
dc.identifier.rimsid39927-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.