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Long-Term Results of Gamma Knife Radiosurgery for Intracranial Meningioma

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dc.contributor.author박용구-
dc.contributor.author장원석-
dc.contributor.author장종희-
dc.contributor.author장진우-
dc.contributor.author장창기-
dc.contributor.author정현호-
dc.date.accessioned2018-03-26T16:45:57Z-
dc.date.available2018-03-26T16:45:57Z-
dc.date.issued2015-
dc.identifier.issn2288-2405-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/156796-
dc.description.abstractBACKGROUND: The predominant treatment modality for meningioma is surgical resection. However, gamma knife radiosurgery is also an important treatment modality for meningioma that is small or cannot be completely removed because of its location. In this study, we evaluated the effectiveness and long-term results of radiosurgical treatment for meningioma in our institution. METHODS: We studied 628 patients (130 men and 498 women) who underwent gamma knife radiosurgery for intracranial meningioma, which is radiologically diagnosed, from Jan 2008 to Nov 2012. We included patients with single lesion meningioma, and followed up after 6 months with imaging, and then at 24 months with a clinical examination. Patients with high-grade meningioma or multiple meningiomas were excluded. We analyzed each of the factors associated with progression free survival. The median patient's age was 56.8 years. Maximal dosage was 27.8 Gy and marginal dosage was 13.9 Gy. RESULTS: The overall tumor control rate was 95%. Twenty-eight patients (4.4%) showed evidence of tumor recurrence. Ninety-eight patients (15%) developed peritumoral edema (PTE) after gamma-knife surgery; two of them (2%) underwent surgical resections due to PTE. Nine patients had craniotomy and tumor removal after gamma knife surgery. CONCLUSION: Gamma knife surgery for intracranial meningioma has proven to be a safe and effective treatment tool with successful long-term outcomes. Gamma knife radiosurgery can be especially effective in cases of remnant meningioma after surgical resection or where PTE is not present.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Brain Tumor Society-
dc.relation.isPartOfBrain Tumor Research and Treatment-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleLong-Term Results of Gamma Knife Radiosurgery for Intracranial Meningioma-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Neurosurgery-
dc.contributor.googleauthorChang Ki Jang-
dc.contributor.googleauthorHyun Ho Jung-
dc.contributor.googleauthorJong Hee Chang-
dc.contributor.googleauthorJin Woo Chang-
dc.contributor.googleauthorYong Gou Park-
dc.contributor.googleauthorWon Seok Chang-
dc.identifier.doi10.14791/btrt.2015.3.2.103-
dc.contributor.localIdA01578-
dc.contributor.localIdA03454-
dc.contributor.localIdA03470-
dc.contributor.localIdA03484-
dc.contributor.localIdA04794-
dc.contributor.localIdA03775-
dc.relation.journalcodeJ00398-
dc.identifier.eissn2288-2413-
dc.identifier.pmid26605265-
dc.subject.keywordMeningioma-
dc.subject.keywordRadiosurgery-
dc.subject.keywordStereotactic-
dc.contributor.alternativeNamePark, Yong Gou-
dc.contributor.alternativeNameChang, Won Seok-
dc.contributor.alternativeNameChang, Jong Hee-
dc.contributor.alternativeNameChang, Jin Woo-
dc.contributor.alternativeNameJang, Chang Ki-
dc.contributor.alternativeNameJung, Hyun Ho-
dc.contributor.affiliatedAuthorPark, Yong Gou-
dc.contributor.affiliatedAuthorChang, Won Seok-
dc.contributor.affiliatedAuthorChang, Jong Hee-
dc.contributor.affiliatedAuthorChang, Jin Woo-
dc.contributor.affiliatedAuthorJang, Chang Ki-
dc.contributor.affiliatedAuthorJung, Hyun Ho-
dc.citation.volume3-
dc.citation.number2-
dc.citation.startPage103-
dc.citation.endPage107-
dc.identifier.bibliographicCitationBrain Tumor Research and Treatment, Vol.3(2) : 103-107, 2015-
dc.identifier.rimsid39924-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers

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