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F-18 Fluoride Positron Emission Tomography-Computed Tomography for Detecting Atherosclerotic Plaques

DC FieldValueLanguage
dc.contributor.author강원준-
dc.date.accessioned2018-03-26T16:45:47Z-
dc.date.available2018-03-26T16:45:47Z-
dc.date.issued2015-
dc.identifier.issn1229-6929-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/156793-
dc.description.abstractA large number of major cardiovascular events occur in patients due to minimal or some lumen narrowing of the coronary artery. Recent biological studies have shown that the biological composition or vulnerability of the plaque is more critical for plaque rupture compared to the degree of stenosis. To overcome the limitations of anatomical images, molecular imaging techniques have been suggested as promising imaging tools in various fields. F-18 fluorodeoxyglucose (FDG), which is widely used in the field of oncology, is an example of molecular probes used in atherosclerotic plaque evaluation. FDG is a marker of plaque macrophage glucose utilization and inflammation, which is a prominent characteristic of vulnerable plaque. Recently, F-18 fluoride has been used to visualize vulnerable plaque in clinical studies. F-18 fluoride accumulates in regions of active microcalcification, which is normally observed during the early stages of plaque formation. More studies are warranted on the accumulation of F-18 fluoride and plaque formation/vulnerability; however, due to high specific accumulation, low background activity, and easy accessibility, F-18 fluoride is emerging as a promising non-invasive imaging probe to detect vulnerable plaque.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Society of Radiology-
dc.relation.isPartOfKOREAN JOURNAL OF RADIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAtherosclerosis/diagnostic imaging*-
dc.subject.MESHAtherosclerosis/pathology-
dc.subject.MESHCoronary Vessels-
dc.subject.MESHFluorodeoxyglucose F18/chemistry-
dc.subject.MESHHumans-
dc.subject.MESHPlaque, Atherosclerotic-
dc.subject.MESHPositron-Emission Tomography*-
dc.subject.MESHTomography, X-Ray Computed*-
dc.titleF-18 Fluoride Positron Emission Tomography-Computed Tomography for Detecting Atherosclerotic Plaques-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Nuclear Medicine-
dc.contributor.googleauthorWon Jun Kang-
dc.identifier.doi10.3348/kjr.2015.16.6.1257-
dc.contributor.localIdA00062-
dc.relation.journalcodeJ02884-
dc.identifier.eissn2005-8330-
dc.identifier.pmid26576114-
dc.subject.keywordAtherosclerosis-
dc.subject.keywordFluoride-
dc.subject.keywordPET-
dc.subject.keywordVulnerable plaque-
dc.contributor.alternativeNameKang, Won Jun-
dc.contributor.affiliatedAuthorKang, Won Jun-
dc.citation.volume16-
dc.citation.number6-
dc.citation.startPage1257-
dc.citation.endPage1261-
dc.identifier.bibliographicCitationKOREAN JOURNAL OF RADIOLOGY, Vol.16(6) : 1257-1261, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers

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