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Updates in the Pathogenesis of Rosacea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이상은 | - |
dc.contributor.author | 이승헌 | - |
dc.contributor.author | 임정민 | - |
dc.date.accessioned | 2018-03-26T16:40:28Z | - |
dc.date.available | 2018-03-26T16:40:28Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 1229-4934 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/156695 | - |
dc.description.abstract | Rosacea is a common, chronic inflammatory disorder of the skin, with central facial erythema and inflammatory papules and pustules as the commonly recognized features. Although the exact pathogenesis of rosacea is unknown, dysregulation of the innate immune system, neurovascular dysregulation and overgrowth of commensal skin organisms are thought to be involved in the pathophysiology of rosacea. Various receptors and mediators, including cathelicidin, endoplasmic reticulum(ER) stress, toll-like receptor(TLR) 2, protease-activated receptor(PAR) 2, transient receptor potential(TRP)s, and mast cells, express important functions in each aspect. They are also intimately connected and form a proinflammatory cascade, which ultimately results in the development of clinical symptoms presented in rosacea. In this review, we briefly summarize key factors and recent studies about the updated pathogenesis of rosacea. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | Korean | - |
dc.publisher | 한국피부장벽학회 | - |
dc.relation.isPartOf | Journal of Skin Barrier Research (한국피부장벽학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Updates in the Pathogenesis of Rosacea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Dermatology | - |
dc.contributor.googleauthor | Jung Min Lim | - |
dc.contributor.googleauthor | Sang Eun Lee | - |
dc.contributor.googleauthor | Seung Hun Lee | - |
dc.contributor.localId | A02826 | - |
dc.contributor.localId | A02931 | - |
dc.contributor.localId | A04652 | - |
dc.relation.journalcode | J01749 | - |
dc.identifier.url | http://www.papersearch.net/thesis/article.asp?KEY=3429812 | - |
dc.subject.keyword | Cathelicidin | - |
dc.subject.keyword | ER stress | - |
dc.subject.keyword | Mast cell | - |
dc.subject.keyword | Rosacea | - |
dc.subject.keyword | TLR2 | - |
dc.subject.keyword | TRPA1 | - |
dc.subject.keyword | TRPV1 | - |
dc.contributor.alternativeName | Lee, Sang Eun | - |
dc.contributor.alternativeName | Lee, Seung Hun | - |
dc.contributor.alternativeName | Lim, Jung Min | - |
dc.contributor.affiliatedAuthor | Lee, Sang Eun | - |
dc.contributor.affiliatedAuthor | Lee, Seung Hun | - |
dc.contributor.affiliatedAuthor | Lim, Jung Min | - |
dc.citation.volume | 17 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 20 | - |
dc.citation.endPage | 26 | - |
dc.identifier.bibliographicCitation | Journal of Skin Barrier Research (한국피부장벽학회지), Vol.17(1) : 20-26, 2015 | - |
dc.identifier.rimsid | 39826 | - |
dc.type.rims | ART | - |
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