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Role of surgical therapy in the management of gestational trophoblastic neoplasia
DC Field | Value | Language |
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dc.contributor.author | 김상운 | - |
dc.contributor.author | 김성훈 | - |
dc.contributor.author | 김영태 | - |
dc.contributor.author | 남은지 | - |
dc.contributor.author | 어경진 | - |
dc.contributor.author | 임가원 | - |
dc.contributor.author | 정영신 | - |
dc.date.accessioned | 2018-01-23T05:49:47Z | - |
dc.date.available | 2018-01-23T05:49:47Z | - |
dc.date.issued | 2015 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/155688 | - |
dc.description.abstract | OBJECTIVE: To evaluate the role of adjuvant surgical procedures in the management of gestational trophoblastic neoplasia (GTN). METHODS: In a retrospective review of medical records at the Severance Hospital, we identified 174 patients diagnosed with GTN between 1986 and 2006. Of the 174 patients, 129 (74%) were assigned to the nonmetastatic group, and 45 (26%) to the metastatic group; of the metastatic group patients, 6 were in the low-risk group and 39 were in the high-risk group. Thirty-two patients underwent 35 surgical procedures as part of the GTN treatment. The procedures included hysterectomy, lung resection, craniotomy, uterine wedge resection, uterine suturing for bleeding, salpingo-oophorectomy, pretherapy dilatation and curettage, adrenalectomy, nephrectomy, and uterine artery embolization. RESULTS: Of the 32 patients who underwent surgical procedures, 28 (87%) survived. Eleven patients underwent surgery for chemoresistant disease after receiving one or more chemotherapy regimens. Twelve patients underwent procedures to control tumor hemorrhage. Nine (81%) of 11 patients with chemoresistant disease survived, and 8 patients who underwent salvage surgery for chemoresistant disease received further chemotherapy. Of 21 patients who underwent hysterectomy, 19 (90%) achieved remission. All of three patients who had resistant foci of choriocarcinoma in the lung achieved remission through pulmonary resection. CONCLUSION: Adjuvant surgical procedures, especially hysterectomy and pulmonary resection for chemoresistant disease, as well as procedures to control hemorrhage, are pivotal in the management of GTN. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | Obstetrics & Gynecology Science | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Role of surgical therapy in the management of gestational trophoblastic neoplasia | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine | - |
dc.contributor.department | Dept. of Obstetrics & Gynecology | - |
dc.contributor.googleauthor | Kyung Jin Eoh | - |
dc.contributor.googleauthor | Young Shin Chung | - |
dc.contributor.googleauthor | Ga Won Yim | - |
dc.contributor.googleauthor | Eun Ji Nam | - |
dc.contributor.googleauthor | Sunghoon Kim | - |
dc.contributor.googleauthor | Sang Wun Kim | - |
dc.contributor.googleauthor | Young Tae Kim | - |
dc.identifier.doi | 10.5468/ogs.2015.58.4.277 | - |
dc.contributor.localId | A00526 | - |
dc.contributor.localId | A00595 | - |
dc.contributor.localId | A00729 | - |
dc.contributor.localId | A01262 | - |
dc.contributor.localId | A04842 | - |
dc.contributor.localId | A03354 | - |
dc.contributor.localId | A04849 | - |
dc.relation.journalcode | J02408 | - |
dc.identifier.pmid | 26217597 | - |
dc.subject.keyword | Adjuvant surgery | - |
dc.subject.keyword | Gestational trophoblastic neoplasia | - |
dc.contributor.alternativeName | Kim, Sang Wun | - |
dc.contributor.alternativeName | Kim, Sung Hoon | - |
dc.contributor.alternativeName | Kim, Young Tae | - |
dc.contributor.alternativeName | Nam, Eun Ji | - |
dc.contributor.alternativeName | Eoh, Kyung Jin | - |
dc.contributor.alternativeName | Yim, Ga Won | - |
dc.contributor.alternativeName | Chung, Young Shin | - |
dc.contributor.affiliatedAuthor | Kim, Sang Wun | - |
dc.contributor.affiliatedAuthor | Kim, Sung Hoon | - |
dc.contributor.affiliatedAuthor | Kim, Young Tae | - |
dc.contributor.affiliatedAuthor | Nam, Eun Ji | - |
dc.contributor.affiliatedAuthor | Eoh, Kyung Jin | - |
dc.contributor.affiliatedAuthor | Yim, Ga Won | - |
dc.contributor.affiliatedAuthor | Chung, Young Shin | - |
dc.citation.volume | 58 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 277 | - |
dc.citation.endPage | 283 | - |
dc.identifier.bibliographicCitation | Obstetrics & Gynecology Science, Vol.58(4) : 277-283, 2015 | - |
dc.identifier.rimsid | 48149 | - |
dc.type.rims | ART | - |
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